710354-60-2

Upstream product

• 645-96-5 Benzeneselenol 
• 710354-66-8 (4S,5R)-2,2,5-Trimethyl-4-((2R,3S)-2-methyl-4-oxo-oxetan-3-ylcarbamoyl)-oxazolidine-3-carboxylic acid 2-trimethylsilanyl-ethyl ester 
• 710354-71-5 2-((1S,2S,3R)-1-tert-Butoxycarbonylamino-2,3-dihydroxy-2-methyl-butyl)-thiazole-4-carboxylic acid ethyl ester 
• 710354-64-6 2-((Z)-(S)-1-tert-Butoxycarbonylamino-2-methyl-but-2-enyl)-thiazole-4-carboxylic acid ethyl ester 
• 710354-63-5 (4S,5R)-2,2,5-Trimethyl-oxazolidine-3,4-dicarboxylic acid 3-(2-trimethylsilanyl-ethyl) ester 
• 80149-80-0 2-(Trimethylsilyl)ethyl 4-nitrophenyl carbonate 
• 710354-62-4 2-((1S,2S,3R)-1-Amino-2-methyl-2,3-bis-triethylsilanyloxy-butyl)-thiazole-4-carboxylic acid ethyl ester 
• 710354-61-3 (4S,5R)-4-[(1R,2S)-1-((R)-1-Carboxy-2-hydroxy-ethylcarbamoyl)-2-phenylselanyl-propylcarbamoyl]-2,2,5-trimethyl-oxazolidine-3-carboxylic acid 2-trimethylsilanyl-ethyl ester 

Downstream Products

• 710354-73-7 4-(1-{4-[1-(4-ethoxycarbonyl-thiazol-2-yl)-2-methyl-2,3-bis-triethylsilanyloxy-butylcarbamoyl]-4,5-dihydro-oxazol-2-yl}-2-phenylselanyl-propylcarbamoyl)-2,2,5-trimethyl-oxazolidine-3-carboxylic acid 2-trimethylsilanyl-ethyl ester 

Relevant academic research and scientific papers

Synthetic studies on thiostrepton family of peptide antibiotics: Synthesis of the pentapeptide segment containing dihydroxyisoleucine, thiazoline and dehydroamino acid

The dihydroxyisoleucine-, thiazoline- and dehydroamino acid-containing pentapeptide of the thiostrepton family of peptide antibiotics was synthesized, which featured the β-lactone opening by phenylselenylation, the vinylzinc addition to the chiral sulfinimine, the Wipf oxazoline-thiazoline conversion method and the oxidative syn-elimination of the phenylseleno group.