71041-29-7Relevant academic research and scientific papers
Modular Synthesis of Functionalized Butenolides by Oxidative Furan Fragmentation
Bao, Jiajing,Tian, Hailong,Yang, Peicheng,Deng, Jiachen,Gui, Jinghan
, p. 339 - 347 (2020)
The development of new chemical transformations to simplify the synthesis of valuable building blocks is a challenging task in organic chemistry and has been the focus of considerable research effort. Here we report a chemical transformation that enables
Urea decomposition: Efficient synthesis of pyrroles using the deep eutectic solvent choline chloride/urea
Hu, Lanfang,Luo, Juan,Lu, Dan,Tang, Qiang
supporting information, p. 1698 - 1701 (2018/04/02)
A simple and efficient method is reported for the synthesis of pyrroles via condensation of a series of tricarbonyl compounds with ammonia, which was generated in situ from decomposition of the deep eutectic solvent choline chloride/urea.
Understanding the Scope of Feist–Bénary Furan Synthesis: Chemoselectivity and Diastereoselectivity of the Reaction Between α-Halo Ketones and β-Dicarbonyl Compounds
Peng, Yi,Luo, Juan,Feng, Qiang,Tang, Qiang
, p. 5169 - 5179 (2016/10/26)
Feist–Bénary furan synthesis, the reaction between α-halocarbonyl and β-dicarbonyl compounds, has been known as an efficient method for generating many different types of furans containing a carbonyl group at C-3. However, it has also been reported that, under similar reaction conditions, intermediate tricarbonyl species could be further converted to alternative furan isomers through the application of a Paal–Knorr synthesis. In this manuscript, we investigate the chemoselectivity and diastereoselectivity of furan synthesis from α-halo ketones and β-dicarbonyl compounds, by carrying out the separation and characterization of the intermediates involved in the reaction. Additionally, a one-pot Feist–Bénary furan synthesis from α-halo ketones and β-dicarbonyl compounds without any base or solvent has also been developed.
