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2,3,7,7a-Tetrahydro-7-methyl-1H-indene-4-carboxylic acid ethyl ester, commonly known as Tretinoin, is a synthetic derivative of vitamin A. It is widely utilized in skincare products due to its ability to enhance cell turnover, prevent the development of new acne lesions, and reduce the appearance of fine lines and wrinkles. Tretinoin also aids in improving skin texture and reversing the effects of sun damage. Furthermore, it has demonstrated efficacy in treating conditions such as psoriasis and photoaging. However, its use may result in skin irritation and increased sensitivity to sunlight, necessitating careful application and the use of sunscreen.

71042-73-4

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71042-73-4 Usage

Uses

Used in Skincare Products:
2,3,7,7a-Tetrahydro-7-methyl-1H-indene-4-carboxylic acid ethyl ester is used as an active ingredient in skincare products for its cell turnover promotion and acne prevention properties. It helps in reducing the appearance of fine lines and wrinkles, improving skin texture, and reversing sun damage.
Used in Treatment of Skin Conditions:
In the Pharmaceutical Industry, 2,3,7,7a-Tetrahydro-7-methyl-1H-indene-4-carboxylic acid ethyl ester is used as a therapeutic agent for treating conditions such as psoriasis and photoaging. Its effectiveness in these applications is attributed to its ability to regulate skin cell functions and promote skin health.
Used in Sun Protection:
Although Tretinoin can cause increased sensitivity to sunlight, it is often used in conjunction with sunscreens to mitigate this effect. The combination of Tretinoin and sunscreens is crucial for protecting the skin from harmful UV rays while undergoing treatment with 2,3,7,7a-Tetrahydro-7-methyl-1H-indene-4-carboxylic acid ethyl ester.

Check Digit Verification of cas no

The CAS Registry Mumber 71042-73-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,0,4 and 2 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 71042-73:
(7*7)+(6*1)+(5*0)+(4*4)+(3*2)+(2*7)+(1*3)=94
94 % 10 = 4
So 71042-73-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H18O2/c1-3-15-13(14)12-8-7-9(2)10-5-4-6-11(10)12/h7,10H,3-6,8H2,1-2H3

71042-73-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 7-methyl-2,3,7,7a-tetrahydro-1H-indene-4-carboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:71042-73-4 SDS

71042-73-4Downstream Products

71042-73-4Relevant academic research and scientific papers

Improved Synthesis of 3-Methylcholanthrene

Tang, Ping Wah,Maggiulli, Cataldo A.

, p. 3429 - 3432 (2007/10/02)

An improved synthesis of 7-methylindan-4-yl 1-naphthyl ketone (3), an important precursor of 3-methylcholanthrene (1), has been developed.The key intermediates for 3, 4-cyano-7-methylindan (2a) and 4-(ethoxycarbonyl)-7-methylindan (2b), were conveniently prepared in high yields by reaction of 1-(1-pyrrolidino)cyclopentene (6) with sorbonitrile (5a) or ethyl sorbate (5b), followed by aromatization with sulfur. 1-Naphthylmagnesium bromide (4b) in the presence of cuprous iodide reacted cleanly with 4-(chloromethanoyl)-7-methylindan (12) to give 3.The Friedel-Crafts acylation of naphthalene with 12 afforded 84percent of 3 and 16percent of β isomer 13.Alternatively, 3 was prepared in 75percent yield by condensation of Grignard reagent 4b with 2a in THF.Thermal annelation of 3 afforded 1 in 41.5percent yield.

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