71049-54-2

Upstream product

• 42822-28-6 methyl O⁴-methyl-α-L-6-deoxy-galactopyranoside 
• 26706-17-2 methyl 6-deoxy-2,3-O-isopropylidene-4-O-methyl-α-L-mannopyranoside 
• 14133-63-2 methyl 2,3-O-isopropylidene-α-L-rhamnoside 
• 107557-56-2 Benzyl-2,3-di-O-benzyl-6-O-tosyl-β-D-galactopyranosid 
• 107557-58-4 Benzyl-2,3-di-O-benzyl-6-desoxy-β-D-galactopyranosid 
• 74801-06-2 benzyl 2,3-di-O-benzyl-4,6-ol-β-D-galactopyranoside 
• 107557-60-8 Benzyl-2,3-di-O-benzyl-6-desoxy-4-O-methyl-β-D-galactopyranosid 

Relevant academic research and scientific papers

BIARYL AMIDES WITH MODIFIED SUGAR GROUPS FOR TREATMENT OF DISEASES ASSOCIATED WITH HEAT SHOCK PROTEIN PATHWAY

Provided are biaryl amides and coumarin-based compounds with modified sugar groups for treatment of diseases associated with heat shock protein pathway. The compounds having the following formulas, wherein variables are as defined herein. Formulae (I), (II), (III), (IV), and (V), Pharmaceutical compositions of the compounds are also provided. These biaryl amides and coumarin-based derivatives with modified sugar groups are useful for treatment and prevention of diseases and disorders, including neurological disorders, such as neurodegenerative diseases and nerve damaging disorders, for example, diabetic peripheral neuropathy.

PHENOLIC EXTRACTIVES FROM ROOT BARK OF PICEA ABIES

Five new compounds, viz., 3,4-dimethoxyphenyl 2-O-(3-O-methyl-α-L-rhamnopyranosyl)-β-D-glucopyranoside, 4'-hydroxyphenacyl β-D-glucopyranoside, (2R,3R)-2,3-dihydro-7-hydroxy-2-(4'-hydroxy-3'-methoxyphenyl)-3-hydroxymethyl-5-benzofuranpropanol 4'-O-(3-O-methyl-α-L-rhamnopyranoside), 1-(4'-hydroxy-3'-methoxyphenyl)-2--1,3-propanediol 4'-O-β-D-xylopyranoside and 3'-O-methylcatechin 7-O-β-D-glucopyranoside, together with several known compounds were isolated from the root bark of Picea abies.The structures were elucidated on the basis of chemical and spectroscopic evidence. - Key words: Picea abies; Pinaceae; root bark; monoaryl glycosides; stilbenes; lignans; flavonoids; proanthocyanidins.

Syntheses of Methyl 4-O-(β-D-Curacosyl)-α-D-curamicoside, the Glycoside of the Disaccharide Moiety E-F of Flambamycin and Isomers

By application of the tetraisopropyldisiloxy function a five-step synthesis of the selectively protected 2,6-di-O-methylmannopyranoside 5a is achieved.Additionally several steps are used to transfer the galactopyranoside 7 into the α-bromide of 4-O-methyl