71094-61-6Relevant academic research and scientific papers
Synthesis of the tetracyclic core (ABCE rings) of daphenylline
Fang, Bowen,Zheng, Huaiji,Zhao, Changgui,Jing, Peng,Li, Huilin,Xie, Xingang,She, Xuegong
, p. 8367 - 8373,7 (2020/10/15)
A concise synthesis of the tetracyclic core (ABCE rings) of daphenylline has been accomplished involving a benzobicyclo[3.3.1] lactam as the key intermediate. This bridged bicyclic intermediate was efficiently constructed via a Bronsted acid promoted intramolecular Friedel-Crafts type Michael addition of a δ-benzyl α,β-unsaturated δ-lactam.
Stereoselective syntheses of four diastereomers of 3,9,12- trihydroxycalamenene via a benzobicyclo[3.3.1] intermediate
Sun, Yongquan,Yu, Binxun,Wang, Xiaolei,Tang, Shibing,She, Xuegong,Pan, Xinfu
supporting information; experimental part, p. 4224 - 4229 (2010/08/22)
The highly stereoselective syntheses of four diastereomers of natural 3,9,12-trihydroxycalamenene are described. The syntheses highlight the utility of an unusual framework of benzobicyclo[3.3.1] lactones, which were accomplished via an intramolecular Friedel-Crafts-type Michael addition of α,β-unsaturated lactones.
