711-30-8Relevant academic research and scientific papers
Lipase-catalyzed asymmetric synthesis of naphtho[2,3-c]furan-1(3H)-one derivatives by a one-pot dynamic kinetic resolution/intramolecular Diels–Alder reaction: Total synthesis of (?)-himbacine
Sugiyama, Koji,Kawanishi, Shinji,Oki, Yasuhiro,Kamiya, Marin,Hanada, Ryosuke,Egi, Masahiro,Akai, Shuji
supporting information, p. 1378 - 1386 (2017/10/06)
One-pot sequential reactions using the acyl moieties installed by enzymatic dynamic kinetic resolution of alcohols have been little investigated. In this work, the acryloyl moiety installed via the lipase/oxovanadium combo-catalyzed dynamic kinetic resolution of a racemic dienol [4-(cyclohex-1-en-1-yl)but-3-en-2-ol or 1-(cyclohex-1-en-1-yl)but-2-en-1-ol] with a (Z)-3-(phenylsulfonyl)acrylate underwent an intramolecular Diels–Alder reaction in a one-pot procedure to produce an optically active naphtho[2,3-c]furan-1(3H)-one derivative (98% ee). This method was successfully applied to the asymmetric total synthesis of (?)-himbacine.
A Mild, Inexpensive and Practical Oxidation of Sulfides
Webb, Kevin S.
, p. 3457 - 3460 (2007/10/02)
Several sulfides have been converted to sulfoxides or sulfones in modest to excellent yields.The oxidant was oxone and the reactions were performed in 12.5percent aqueous acetone and buffered to pH 7.5-8.0 with sodium bicarbonate.
Pharmaceutical compositions containing acrylic acid derivatives and their use in the medicine
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, (2008/06/13)
Known acrylic acid derivatives of formula wherein, n is an integer of from 0 to 2,R represents a hydrogen, an alkaline or an alkaline earth metal atom, or a C1 4alkyl-group, and, R1 represents a hydrogen or a halogen atom or a C
