71109-13-2Relevant academic research and scientific papers
Acylation of Heterocycles with Carbonic Acid Derivatives. I. Kinetics and Mechanism of the Reaction of 2-Aminobenzimidazoles with Aryl Cyanates
Glatt, Hans Horst,Bacaloglu, Ilse,Ky, Truong The,Boeriu, Carmen,Bacaloglu, Radu,et. al.
, p. 803 - 808 (2007/10/02)
The second order rate constants for the reaction of 2-amino-benzimidazoles (2-ABI) with aryl cyanates forming 2-amino-benzimidazole aryl ester imide 3 have been determined in dependence on substituent effects by u. v. measurements.The results are interpreted by a six-membered cyclic transition state in which the electrophilic attack of the cyanate on the endocyclic N atom is catalyzed by an H bridge interaction of the exocyclic amino group of 2-ABI with the OCN group.
