7111-89-9

Usage

Uses

Used in Pharmaceutical Industry:
(CHLOROFLUOROMETHYL)BENZENE is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, (CHLOROFLUOROMETHYL)BENZENE serves as an intermediate in the production of agrochemicals, helping to create compounds that protect crops and enhance agricultural productivity.
Used in Plastics Production:
(CHLOROFLUOROMETHYL)BENZENE is utilized in the manufacturing process of plastics, contributing to the formation of materials with desired properties for various applications.
Used in Resins Production:
(CHLOROFLUOROMETHYL)BENZENE is employed in the production of resins, which are used in coatings, adhesives, and composite materials across different industries.
Used in Solvents Production:
It is also used in the creation of solvents, which are essential in various chemical processes and industries for their ability to dissolve other substances.
Used in Chemical Research:
(CHLOROFLUOROMETHYL)BENZENE may be utilized as a solvent and in chemical research, providing a basis for scientific exploration and the advancement of chemical knowledge.
It is crucial to handle (CHLOROFLUOROMETHYL)BENZENE with care due to its potential hazards if not used properly, ensuring safety in its applications across various industries.

Upstream product

• 350-50-5 benzyl fluoride 
• 98-87-3 benzylidene dichloride 

Relevant academic research and scientific papers

Catalytic fluorination of dichloromethylbenzene by HF in liquid phase. Preparation of fluorinated building blocks

The selective fluorination by successive Cl/F exchanges of the dichloromethylbenzene, was studied in the presence of HF as the fluorinating agent. The influence of the presence of a catalyst or a basic solvent (such as dioxane, pyridine, tributylphosphate

Microwave-assisted aliphatic fluorine-chlorine exchange using triethylamine trihydrofluoride (TREAT-HF)

Aliphatic fluorine-chlorine exchange reactions can be performed under microwave conditions using TREAT-HF as a mild and selective fluorination reagent. The highly polar TREAT-HF couples efficiently with microwave irradiation and reaction temperatures of 250 °C can be reached within 30 s. Under these conditions dichloromethyl- and trichloromethyl substrates can be converted into the corresponding fluoro analogs within 5 min. In order to prevent corrosion of borosilicate reaction vessel at high temperatures the use of sintered silicon carbide microwave vials is introduced.

Nitrogen-based halogenating agents and process for preparing halogen-containing compounds

Disclosed are a fluorinating agent represented by the general formula (1): wherein R1to R4are a substituted or unsubstituted, saturated or unsaturated alkyl group or a substituted or unsubstituted aryl group, and can be the same or different; R1and R2or R3and R4can bond to form a ring including a nitrogen atom or a nitrogen atom and other hetero atoms; or R1and R3can bond to form a ring including a nitrogen atom or a nitrogen atom and other hetero atoms, for example: a preparation process of the fluorinating agent and a process for preparing fluorine compounds by reacting various compounds with the fluorinating agent. The invention has also disclosed that the fluorinating agent is very effective for fluorinating oxygen containing functional compounds.

MECHANISMS OF FREE-RADICAL REACTIONS. XX. REACTIVITY IN THE FREE-RADICAL HALOGENATION REACTIONS OF ARYLFLUOROALKANES

The free-radical chlorination and bromination of meta- and para-substituted benzyl fluorides and 1,1-difluoro-2-phenylethane and also the chlorination of 1-fluoro-2-arylethanes by phenylchloroiodonium chloride and the bromination of meta- and para-substituted benzyl bromides were studied by the method of competing reactions.In all cases a good correlation is observed between log krel and the Brown ?+ constants.In cases where change in the reactivity in the transition from one reaction series to another is due mainly to the polar effect of the substituent whilethe selectivity is measured in relation to the polar effect direct relationships are observed between the reactivity and the selectivity.