71121-80-7

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 17422-74-1 3-Formylchromone 
• 445291-56-5 2-(N-methyl-N-phenyl)aminochromone-3-carboxaldehyde 
• 76369-08-9 3-(2-Aminophenyliminomethyl)-chromone 
• 71121-70-5 6,11-dihydro<1>benzopyrano<2,3-b><1,5>benzodiazepin-13(5aH)-one 
• 17422-79-6 2-(4-oxo-4H-1-benzopyran-3-yl)-1,3-dioxolane 

Relevant academic research and scientific papers

2-(N-Methylanilino)-3-formylchromone - A versatile synthon for incorporation of chromone moiety in a variety of heterocyclic systems and macrocycles through reactions with bifunctional nucleophiles

Reactions of 2-(N-methylanilino)-3-formylchromones with a number of bifunctional nucleophiles, involving substitution of N-methylanilino moiety and/or condensations with 3-formyl function have provided an easy access to a variety of potentially biologically active hetero-annelated chromones, novel macrocycles, and tetradentate ligands having intact chromone moiety.

Hetericyclic Systems. Part 14. Condensation Reactions of 2-(4-Oxo-4H-1-benzopyran-3-yl)-1,3-dioxolane

Nitrogen nucleophiles under 1,4-addition with the title acetal (4; R=H, Me, and Cl) to give an intermediate that ultimately produces in most cases the same product as is obtained from the corresponding aldehyde (3) under similar conditions.Thus, compound