71125-39-8

Basic information

• Product Name: MELOXICAM SODIUM SALT HYDRATE
• Synonyms: MELOXICAM SODIUM SALT HYDRATE;4-hydroxy-2-methyl-n-(5-methyl-2-thiazolyl)-2h-1,2-benzothiazine-3-carboxamide 1,1-dioxide sodium hydrate;Meloxicam hydrate sodium salt;Metacam hydrate sodium salt, Mobec hydrate sodium salt, UH-AC 62XX hydrate sodium salt, 4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide hydrate sodium;Meloxicam sodium salt hydrate,4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide sodium hydrate, Metacam sodium salt hydrate, Mobec sodium salt hydrate, UH-AC 6;Metacam sodium salt hydrate;Mobec sodium salt hydrate;UH-AC 62XX sodium salt hydrate
• CAS NO: 71125-39-8
• Molecular Formula: C14H12N3NaO4S2
• Molecular Weight: 0
• Mol File: 71125-39-8.mol
• Article Data: 0

Chemical Properties

• Appearance: light yellow to dark yellow/
• Storage Temp.: room temp
• Solubility: DMSO: soluble5mg/mL, clear
• CAS DataBase Reference: MELOXICAM SODIUM SALT HYDRATE(CAS DataBase Reference)
• NIST Chemistry Reference: MELOXICAM SODIUM SALT HYDRATE(71125-39-8)
• EPA Substance Registry System: MELOXICAM SODIUM SALT HYDRATE(71125-39-8)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 71125-39-8(Hazardous Substances Data)

Usage

Uses

Meloxicam sodium salt hydrate has been used: as a cyclooxygenase-2 (COX-2) inhibitor in solid Ehrlich tumoras an alternative to diclofenac nonsteroidal anti-inflammatory drugs (NSAID) to treat vulturesas a reference standard in liquid chromatography electrospray ionisation mass spectrometry (LC-ESI/MS)to test its effect on prostaglandin (PGE2) production in lipopolysaccharide (LPS)-induced COX-2 protein expression in RAW246.7 cells

Biochem/physiol Actions

Meloxicam, a member of the oxicam family, is a non-steroidal anti-inflammatory drug (NSAID). It is synthesized from piroxicam with aryl and the pyridyl ring substitution. Meloxicam is a cyclooxygenase-2 (COX-2) inhibitor, it may be useful in treating inflammation and pain. Meloxicam has been shown to stop thymulin-induced increas in concentration of cytokines and Nerve growth factor?(NGF) in the liver of rats. Meloxicam also suppresses tumor growth and may be capable of antagonizing cachexia?in vitro. It promotes apoptosis in hepatocellular carcinoma.