71135-80-3

Usage

Uses

Used in Pharmaceutical Industry:
9,10-Dihydro-7-methoxy-3,5-phenanthrenediol is used as a pharmaceutical agent for its potential antimicrobial properties. Due to its structural similarity to orchid phytoalexin, it may exhibit similar antimicrobial effects and could be utilized in the development of new antimicrobial drugs or treatments.
Used in Research:
9,10-Dihydro-7-methoxy-3,5-phenanthrenediol is used as a research compound for studying its chemical properties, potential applications, and mechanisms of action. This can contribute to a better understanding of its potential uses in various fields, such as medicine, agriculture, or environmental science.

Upstream product

• 71135-79-0 cannabispiradienone-A 
• 883-07-8 6,8-dimethoxy-3,4-dihydro-2H-naphthalen-1-one 
• 99050-45-0 8-Benzyloxy-6-methoxy-1-oxo-2-(3-oxo-butyl)-1,2,3,4-tetrahydro-naphthalene-2-carbaldehyde 
• 99050-47-2 8-Benzyloxy-6-methoxy-2-(3-oxo-butyl)-3,4-dihydro-2H-naphthalen-1-one 
• 99050-44-9 3,4-Dihydro-2-(hydroxymethylene)-6-methoxy-8-(phenylmethoxy)-1(2H)-naphthalenone 
• 99050-37-0 1-Diazo-4-(3,5-dimethoxy-phenyl)-butan-2-one 
• 99050-43-8 8-Benzyloxy-6-methoxytetralone 
• 99050-38-1 4-(3,5-Dimethoxyphenyl)butyric acid methyl ester 
• 99050-36-9 3-(3,5-dimethoxyphenyl) propionic acid chloride 
• 99050-42-7 8-hydroxy-6-methoxy-1-tetralone 
• 717-94-2 3-(3,5-dimethoxyphenyl)propionic acid 
• 91555-31-6 4-(3,5-dimethoxyphenyl)butanoic acid 
• 76842-74-5 O-methylcannabispiradienone 
• 99050-46-1 5-Benzyloxy-7-methoxy-1,9,10,10a-tetrahydro-2H-phenanthren-3-one 

Relevant academic research and scientific papers

Total Synthesis of the Spirans of Cannabis: Cannabispiradienone, Cannabispirenone-A and -B, Cannabispirone, α- and β-Cannabispiranols and the Dihydrophenanthrene Cannithrene-1

O-Methylcannabispirenone has been synthesised (57percent overall from 3,5-dimethoxycinnamic acid) via 5,7-dimethoxyindanone, p-tolylsulphonylmethyl isocyanide conversion into the 1-nitrile, alkylation with 1-iodo-3,3-ethylenedioxybutane, deacetalisation, and spirocyclisation. 5,7-Dimethoxyindanone is 7-deprotected by boron trichloride with high selectivity, and re-protected as the methoxyethoxymethyl ether: following the above route, finally deprotecting by boron trichloride, gives cannabispirenone-A (2) in 21percent overall yield.O-Methylcannabispirenone can be demethylated to give (2) by lithium 1,1-dimethylethanethiolate: demethylation with boron tribromide gives cannabispirenone-B (3).Hydrogenation of synthetic cannabispirenone-A gives cannabispirone (4), reduced by borohydride to the epimeric α-(6) and β-(5) cannabispiranols, separated by h.p.l.c.Dehydrogenation of O-methylcannabispirenone with dichlorodicyanobenzoquinone, followed by lithium 1,1-dimethylethanethiolate demethylation, gives cannabispiradienone (1).Under acidic conditions, the latter undergoes dienone-phenol rearrangement to give cannithrene-1 (8), thus completing the total synthesis of the spiro-cannabinoid group of natural products discussed in the preceding paper.The unsubstituted cannabispirenone parent has also been synthesised.

Natural Products of Thailand High Δ1-THC -Strain Cannabis. The Bibenzyl-spiran-dihydrophenanthrene Group: Relations with Cannabinoids and Canniflavones

Since non-cannabinoids may influence the pharmacological profile of Cannabis-leaf drug, a detailed examination of the acidic-fraction from leaf extractive has been made.Twelve non-cannabinoids have been isolated crystalline from a single high Δ1/sup