71172-28-6 Usage
Purpose
Treatment of epileptic seizures
Classification
Anticonvulsant medication
Mechanism
Reduces the excitability of neurons in the brain
Structural Relation
Derivative of pyridine, related to phenytoin
Administration
Orally in tablet form
Absorption
Rapidly absorbed in the gastrointestinal tract
Half-life
Relatively long, allowing for once or twice daily dosing
Side Effects
Dizziness, drowsiness, nausea, adverse effects on liver and blood cells
Monitoring
Close monitoring by a healthcare professional is important.
Check Digit Verification of cas no
The CAS Registry Mumber 71172-28-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,1,7 and 2 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 71172-28:
(7*7)+(6*1)+(5*1)+(4*7)+(3*2)+(2*2)+(1*8)=106
106 % 10 = 6
So 71172-28-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H15NO/c1-3-12-8-7-10-6-4-5-9(2)11-10/h4-6H,3,7-8H2,1-2H3
71172-28-6Relevant articles and documents
Radical Hydroarylation of Functionalized Olefins and Mechanistic Investigation of Photocatalytic Pyridyl Radical Reactions
Seath, Ciaran P.,Vogt, David B.,Xu, Zihao,Boyington, Allyson J.,Jui, Nathan T.
, p. 15525 - 15534 (2018)
We report the photoredox alkylation of halopyridines using functionalized alkene and alkyne building blocks. Selective single-electron reduction of the halogenated pyridines provides the corresponding heteroaryl radicals, which undergo anti-Markovnikov addition to the alkene substrates. The system is shown to be mild and tolerant of a variety of alkene and alkyne subtypes. A combination of computational and experimental studies support a mechanism involving proton-coupled electron transfer followed by medium-dependent alkene addition and rapid hydrogen atom transfer mediated by a polarity-reversal catalyst.
