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8-Benzyl-1-propyl-1,3,8-triaza-spiro[4.5]dec-2-en-4-one is a complex organic compound with a molecular formula of C16H24N3O. It is a heterocyclic compound, featuring a spiro structure with a triaza core and a 4.5-decane backbone. The compound is characterized by the presence of a benzyl group attached to the 8th carbon and a propyl group on the 1st carbon. The 2-en-4-one functional group indicates the presence of a double bond between the 2nd and 3rd carbons and a ketone group at the 4th carbon. This chemical is primarily of interest in the field of organic chemistry and may have potential applications in the synthesis of pharmaceuticals or other specialty chemicals.

7118-21-0

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7118-21-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7118-21-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,1 and 8 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 7118-21:
(6*7)+(5*1)+(4*1)+(3*8)+(2*2)+(1*1)=80
80 % 10 = 0
So 7118-21-0 is a valid CAS Registry Number.

7118-21-0Downstream Products

7118-21-0Relevant academic research and scientific papers

Synthesis and characterization of pseudopeptide bradykinin B2 receptor antagonists containing the 1,3,8-triazaspiro[4.5]decan-4-one ring system

Mavunkel, Babu J.,Lu, Zhijian,Goehring, R. Richard,Lu, Songfeng,Chakravarty, Sarvajit,Perumattam, John,Novotny, Elizabeth A.,Connolly, Maureen,Valentine, Heather,Kyle, Donald J.

, p. 3169 - 3173 (2007/10/03)

A series of pseudopeptides containing alkyl-, cycloalkyl-, aryl-, and aralkyl-substituted 1,3,8-triazaspiro[4.5]decan-4-one-3-acetic acids as amino acid surrogates to replace the Pro2-Pro3-Gly4-Phe5 section of the peptide bradykinin B2 receptor antagonist [Pro3, Phe5]HOE 140 (D-Arg0-Arg1- Pro2-Pro3-Gly4-Phe5-Ser6-D-Tic7-Oic8-Arg9) were prepared. These psuedopeptides were examined in vitro for their B2 receptor affinities as well as for their ability to block bradykinin mediated actions in vivo. Two compounds in particular, NPC 18521 (I) and NPC 18688 (V) were quite potent in these latter assays, indicating that a significant portion of this prototypical second generation decapeptide antagonist can be replaced with a more compact nonpeptide molecule.

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