71189-30-5

Basic information

• Product Name: Benzo[b]thiophene-4-ol, 4,5,6,7-tetrahydro-
• Synonyms: 4-hydroxy-4,5,6,7-tetrahydrobenzo[b]thiophene
• CAS NO: 71189-30-5
• Molecular Formula: C8H10OS
• Molecular Weight: 154.22900
• Mol File: 71189-30-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzo[b]thiophene-4-ol, 4,5,6,7-tetrahydro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzo[b]thiophene-4-ol, 4,5,6,7-tetrahydro-(71189-30-5)
• EPA Substance Registry System: Benzo[b]thiophene-4-ol, 4,5,6,7-tetrahydro-(71189-30-5)

Safety Data

• Hazardous Substances Data: 71189-30-5(Hazardous Substances Data)

Upstream product

• 13414-95-4 4-keto-4,5,6,7-tetrahydrothianaphthene 
• 7732-18-5 water 

Downstream Products

• 13414-95-4 4-keto-4,5,6,7-tetrahydrothianaphthene 
• 58095-31-1 4,5,6,7-Tetrahydro-7-oxobenzothien-4-ylharnstoff 

Relevant articles and documents

Chemoselective Oxidation of Equatorial Alcohols with N-Ligated λ3-Iodanes

The site-selective and chemoselective functionalization of alcohols in complex polyols remains a formidable synthetic challenge. Whereas significant advancements have been made in selective derivatization at the oxygen center, chemoselective oxidation to the corresponding carbonyls is less developed. In cyclic systems, whereas the selective oxidation of axial alcohols is well known, a complementary equatorial selective process has not yet been reported. Herein we report the utility of nitrogen-ligated (bis)cationic λ3-iodanes (N-HVIs) for alcohol oxidation and their unprecedented levels of selectivity for the oxidation of equatorial over axial alcohols. The conditions are mild, and the simple pyridine-ligated reagent (Py-HVI) is readily synthesized from commercial PhI(OAc)2 and can be either isolated or generated in situ. Conformational selectivity is demonstrated in both flexible 1,2-substituted cyclohexanols and rigid polyol scaffolds, providing chemists with a novel tool for chemoselective oxidation.

Chiral spiroaminoborate ester as a highly enantioselective and efficient catalyst for the borane reduction of furyl, thiophene, chroman, and thiochroman-containing ketones

Prochiral heteroaryl ketones containing furan, thiophene, chroman, and thiochroman moieties were successfully reduced in the presence of 1-10 mol % of spiroaminoborate ester 1 with different borane sources to afford non-racemic alcohols in up to 99% ee. In addition, modest enantioselectivity, around 80% ee, was achieved in the reduction of linear α,β-unsaturated heteroaryl ketones.

Antiglaucoma thieno-thiopyran and thieno-thiepin sulfonamide derivatives, compositions, and method of use thereof

Aromatic sulfonamides with a saturated heterocycle fused thereto are carbonic anhydrase inhibitors useful in the treatment of elevated intraocular pressure.