712-80-1

Basic information

• Product Name: 2-(4-DIMETHYLAMINOPHENYL)THIAZOLIDINE
• Synonyms: IFLAB-BB F1912-0006;2-(4-DIMETHYLAMINOPHENYL)THIAZOLIDINE;N,N-DIMETHYL-4-(1,3-THIAZOLAN-2-YL)ANILINE;N,N-DIMETHYL-N-[4-(1,3-THIAZOLIDIN-2-YL)PHENYL]AMINE;N,N-Dimethyl-4-(1,3-thiazolidin-2-yl)aniline;dimethyl-(4-thiazolidin-2-ylphenyl)amine
• CAS NO: 712-80-1
• Molecular Formula: C₁₁H₁₆N₂S
• Molecular Weight: 208.32
• Mol File: 712-80-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 139-141
• Boiling Point: 365.2 °C at 760 mmHg
• Flash Point: 174.7 °C
• Appearance: /
• Density: 1.117 g/cm³
• Vapor Pressure: 1.6E-05mmHg at 25°C
• Refractive Index: 1.603
• CAS DataBase Reference: 2-(4-DIMETHYLAMINOPHENYL)THIAZOLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-DIMETHYLAMINOPHENYL)THIAZOLIDINE(712-80-1)
• EPA Substance Registry System: 2-(4-DIMETHYLAMINOPHENYL)THIAZOLIDINE(712-80-1)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 712-80-1(Hazardous Substances Data)

Usage

Uses

Dimethyl-(4-thiazolidin-2-yl-phenyl)-amine is a reactant in the ring-?chain tautomerism in 1,?3-?thiazolidines

InChI:InChI=1/C11H16N2S/c1-13(2)10-5-3-9(4-6-10)11-12-7-8-14-11/h3-6,11-12H,7-8H2,1-2H3

Upstream product

• 156-57-0 2-mercaptoethylamine hydrochloride 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 60-23-1 Cysteamine 

Downstream Products

• 79661-90-8 2-(p-(dimethylamino)phenyl)-N-acetyl-1,3-thiazolidine 

Relevant articles and documents

Evolution of thiazolidine-based blockers of human Kv1.5 for the treatment of atrial arrhythmias

Blockade of the Kv1.5 ion channel is a potentially atrial-selective avenue for the treatment of atrial fibrillation and atrial flutter. The development and biological evaluation of a series of thiazolidine-based blockers of Kv1.5 is described.

Comparative radioprotective activity of various pentagonal compounds with two heteroatomes

Various heterocyclic compounds with two heteroatomes were synthesized and their potential radioprotective activity was tested. This study shows the interest of phenylthiazolidines derivatives in chemical radioprotection.