71202-27-2Relevant academic research and scientific papers
Benzene ring assembly promoted by a camphor derived palladium complex
Carvalho, M. Fernanda N.N.,Almeida, Fernanda M.T.,Galv?o, Adelino M.,Pombeiro, Armando J.L.
, p. 143 - 147 (2007/10/03)
Trans -[PdCl2L2] (1, L=3-NNMe2 C10H14O), under mild reaction conditions, acts as a catalyst for the cyclic trimerization of alkynes. The best performance is achieved for the reaction with PhC≡CMe that affords 1,3,5-trimethyl-2,4,6-triphenyl benzene with high activity and selectivity (ca. 99%). As a general trend the catalytic activity is higher for internal (PhC≡CMe, PhC≡CPh) than for terminal alkynes (HC≡CPh, HC≡CtBu, HC≡CCO2Me). Under more drastic experimental conditions the reaction of 1 with PhC≡CPh yields trans-[PdCl2(PhC≡CPh)2] and no catalytic activity is observed. The molecular structure of 1,3,5-trimethyl-2,4,6-triphenyl benzene was confirmed by X-ray diffraction analysis. The molecules were characterized by 1H- and 13C-NMR spectroscopies, FAB-MS and, in some cases, elemental analyses.
Phosphoric anhydride in the synthesis of monosubstituted ketenes and related dimers
Zavlin, P. M.,Efremov, D. A.,Essentseva, N. S.,Tebby, J. C.
, p. 529 - 532 (2007/10/03)
Monosubstituted ketenes and related condensation products, including phosphorylated, were obtained by the action of phosphoric anhydride on ethyl esters of monosubstituted acetic and malonic acids.
The Phosphorylation of Organic Compounds by Phosphoric Anhydride. Part 3. Synthesis of Monosubstituted Ketenes in the Reaction of Esters with Phosphoric Anhydride and cyclotrimerization of these Ketenes
Efremov, Dimitry A.,Zavlin, Pavel M.,Essentseva, Nataly S.,Tebby, John C.
, p. 3163 - 3168 (2007/10/02)
Monosubstituted ketenes 1 have been synthesized from substituted acetic esters 2 by elimination of alcohol under the action of phosphoric anhydride.The ketenes undergo cyclotrimerization to give substituted phloroglucinols (1,3,5-trihydroxybenzenes) 3 and their phosphorylated derivatives.
