712281-35-1Relevant academic research and scientific papers
Targeting the polyamine pathway with transition-state analogue inhibitors of 5′-methylthioadenosine phosphorylase
Evans, Gary B.,Furneaux, Richard H.,Schramm, Vern L.,Singh, Vipender,Tyler, Peter C.
, p. 3275 - 3281 (2004)
The polyamine biosynthetic pathway is a therapeutic target for proliferative diseases because cellular proliferation requires elevated levels of polyamines. A byproduct of the latter stages of polyamine biosynthesis (the synthesis of spermidine and spermi
