71243-12-4

Basic information

• Product Name: Ethanone, 1-(2,4-dihydroxy-3-iodophenyl)-
• CAS NO: 71243-12-4
• Molecular Formula: C8H7IO3
• Molecular Weight: 278.046
• Mol File: 71243-12-4.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(2,4-dihydroxy-3-iodophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(2,4-dihydroxy-3-iodophenyl)-(71243-12-4)
• EPA Substance Registry System: Ethanone, 1-(2,4-dihydroxy-3-iodophenyl)-(71243-12-4)

Safety Data

• Hazardous Substances Data: 71243-12-4(Hazardous Substances Data)

Upstream product

• 89-84-9 2',4'-dihydroxy-4-acetophenone 

Downstream Products

• 6515-05-5 2',4'-bis(methoxymethoxy)acetophenone 
• 1449202-17-8 1-(3-iodo-2,4-bis(methoxymethoxy)phenyl)ethanone 
• 1544322-59-9 (E)-1-(3-iodo-2,4-bis(methoxymethoxy)phenyl)-3-(4-(methoxymethoxy)phenyl)prop-2-en-1-one 
• 41299-70-1 (E)-1-(2-hydroxy-4-methoxy-3-(3-methylbuta-1,3-dienyl)phenyl)ethanone 
• 103441-61-8 1-(2-hydroxy-3-iodo-4-methoxyphenyl)ethanone 
• 62949-76-2 xanthoangelol 
• 54676-49-2 isobavachalcone 
• 1544322-63-5 (E)-1-(3-((E)-3,7-dimethylocta-2,6-dien-1-yl)-2,4-bis(methoxymethoxy)phenyl)-3-(4-(methoxymethoxy)phenyl)prop-2-en-1-one 
• 1449202-18-9 (E)-1-(2,4-bis(methoxymethoxy)-3-(3-methylbut-2-en-1-yl)phenyl)-3-(4-(methoxymethoxy)phenyl)prop-2-en-1-one 
• 1292793-49-7 2',4,4'-trimethoxy-3'-[(1E)-3-methylbut-1,3-dien-1-yl]chalcone 

Relevant articles and documents

Exploring biological activity of 4-oxo-4h-furo[2,3-h]chromene derivatives as potential multi-target-directed ligands inhibiting cholinesterases, β-secretase, cyclooxygenase-2, and lipoxygenase-5/15

A series of 5-oxo-5H-furo[3,2-g]chromene-6-carbaldehydes and their hydrazone derivatives were evaluated as potential multi-target-directed ligands in vitro against cholinesterases, β-secretase, cyclooxygenase-2, and lipoxygenase-15 (LOX-15), as well as fo

Model studies on construction of the oxabicyclic [3.3.1] core of the mulberry Diels-Alder adducts morusalbanol A and 441772-64-1

Preparation of the oxabicyclic [3.3.1] cores of morusalbanol A and 441772-64-1 was achieved via the intramolecular cyclization of cis-trans (endo) mulberry Diels-Alder adducts. The latter were derived from a hydrogen bond-assisted regioselective Diels-Alder reaction between a chalcone dienophile and a dehydroprenyl diene. Results from these studies provide important insights into the syntheses of morusalbanol A and related mulberry Diels-Alder adducts.

Concise synthesis of prenylated and geranylated chalcone natural products by regiospecific iodination and Suzuki coupling reactions

Four natural chalcones bearing prenyl or geranyl groups, i.e., isobavachalcone (1), bavachalcone (2), xanthoangelol (3), and 2′,4′,4-trihydroxy-5′-geranylchalcone (isoxanthoangelol, 4) were synthesized by using a regio-selective iodination and the Suzuki coupling reaction as key steps. Among them, the first total synthesis of 2′,4′,4-trihydroxy-5′-geranylchalcone was achieved in 36% overall yield. Comparing with the reported methods based on C-alkylation or O-alkylation followed by Claisen rearrangement to introduce the side chain, this new strategy capitalizes on a precious regiochemical control during iodination. The overall yields for the synthesis of the first three chalcones were improved from 17% to 53%, 12% to 35%, and 28% to 50%, respectively.