71253-57-1

Upstream product

• 87514-10-1 α-chloropropyl phenyl sulfide 
• 107-12-0 propiononitrile 
• 108-98-5 thiophenol 
• 96-22-0 pentan-3-one 
• 874-79-3 phenyl(propyl)sulfide 

Downstream Products

• 93338-72-8 2-ethyl-2-phenylsulfanylbutanenitrile 
• 103409-53-6 4,5-Dimethyl-3-phenylsulfanyl-pentadecan-7-one 
• 115993-75-4 4-ethyl-4-(phenylthio)-1-hexene 
• 103409-51-4 5-Methyl-4-phenyl-6-phenylsulfanyl-octan-2-one 
• 103409-52-5 5-Methyl-6-phenylsulfanyl-octan-2-one 
• 103409-62-7 3-(2-Methyl-3-phenylsulfanyl-pentyl)-heptane-2,6-dione 
• 103409-44-5 2-Methyl-1-phenyl-3-phenylsulfanyl-pentan-1-ol 
• 106918-93-8 3-Ethyl-1-phenyl-3-phenylsulfanyl-pentan-1-one 

Relevant academic research and scientific papers

Synthesis of α-methylene-β-hydroperoxy sulfoxides by regioselective photooxygenation (Schenck Reaction) of racemic vinyl sulfoxides

The β-hydroperoxy vinyl sulfoxides 3 were synthesized in good to excellent yields by regioselective photooxygenation of racemic vinyl sulfoxides 2. Moderate diastereoselectivities were observed in the ene reaction of singlet oxygen (Schenck Reaction) with

A New Syntethic Route to Vinyl Sulfides Utilizing the Reaction of (Phenylthio)carbenes with Nitrile Anions

Reactions of nitrile anion (LiCR2R3CN) and (phenylthio)carbenes generated from 1-chloroalkyl phenyl sulfides (R1CH(Cl)SPh) 2a-e by the action of n-BuLi have been shown to be a useful synthetic route to vinyl sulfides (PhSC(R1)=CR2R3) 3a-k (34-91percent).The nucleophilic attack of the nitrile anion on the carbenic species gave the presumed intermediate β-(phenylthio)-β-lithionitrile, which eliminated LiCN to give the expected vinyl sulfides.The application of the present reaction to the synthesis of cyclic vinyl sulfides was successful: the decomposition of the dianion ofω,ω-bis(phenylthio)alkanenitriles (8b, 8c, 11, and 14) affording the corresponding 1-(phenylthio)cycloalkenes (9, 10, 12, and 15) in 12-87percent yields.