713-62-2

Usage

Uses

Used in Pharmaceutical Synthesis:
4-(1,1,2,2-TETRAFLUOROETHOXY)ANILINE is used as a key intermediate in the synthesis of analogs of riluzole (R510000), which is a blocker of excitatory amino acid mediated neurotransmission. This application is significant in the development of treatments for neurological disorders where neurotransmission regulation is crucial.
In the pharmaceutical industry, the unique properties of 4-(1,1,2,2-TETRAFLUOROETHOXY)ANILINE, such as its fluorinated ethoxy group, can contribute to the enhancement of drug candidates' bioavailability, metabolic stability, and target specificity. This makes it a valuable component in the design and synthesis of new drugs with improved therapeutic profiles.

Upstream product

• 116-14-3 polytetrafluoroethylene 
• 59651-96-6 N-(cyclohexylidene)-4-hydroxyaniline 

Downstream Products

• 58139-97-2 C₁₈H₁₁F₈N₅O₂ 
• 27954-35-4 C₁₁H₁₂F₄N₂O₃ 
• 79930-77-1 2,4-dinitro-N-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]-6-(trifluoromethyl)benzenamine 
• 155431-83-7 1-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]-2(1H,3H)-imidazolone 
• 114622-37-6 N-(4-tetrafluoroethoxyphenyl)cyanoacetamide 
• 343860-57-1 [1-(4-Chloro-benzoyl)-2-methyl-5-(1,1,2,2-tetrafluoro-ethoxy)-1H-indol-3-yl]-acetic acid benzyl ester 
• 344238-56-8 [2-Methyl-5-(1,1,2,2-tetrafluoro-ethoxy)-1H-indol-3-yl]-acetic acid benzyl ester 
• 155432-16-9 4-[4-(1,1,2,2-Tetrafluoroethoxy)phenyl]semicarbazide 
• 168969-27-5 4-(1,1,2,2-tetrafluoroethoxy)phenylhydrazine 
• 28002-01-9 1,1-Dimethyl-3-[4-(1,1,2,2-tetrafluoro-ethoxy)-phenyl]-urea 

Relevant academic research and scientific papers

Triazole and imidazole compounds and their use as antifungal therapeutic agents

The present invention provides an azole compound represented by the formula (I): STR1 wherein Ar is an optionally-substituted phenyl group; R1 and R2 are, the same or different, a hydrogen atom or a lower alkyl group, or R1/sup

Cyanoacetamido-derivatives having a fungicidal activity

A method of fighting fungus infections by using compounds having the formula: STR1 wherein: R is H, a C1 -C4 alkyl, an alkenyl, or an alkynyl radical; n is 1 or 2; A represents a C1 -C6 alkylene bridge, an arylene or a heterocyclic bridge; X represents O, S, SO, SO2 ; and R1 is selected from the group consisting of C1 -C6 alkyl radicals, a phenyl radical, optionally substituted, polyfluoroalkyl radicals containing from 1 to 4 carbon atoms and at least 2 fluorine atoms, polyfluoroalkenyl radicals containing from 2 to 4 carbon atoms and at least 2 fluorine atoms, but excluding compounds having the formula (I) wherein A is an alkylene radical, n is 2, and R1 is a C1 -C6 alkyl radical.

Urea derivatives and their use as herbicides

Compounds, useful as herbicides, of the formula SPC1 Wherein R1 is haloalkyl, halocycloalkyl, haloalkenyl, or halocycloalkenyl; n1 is 1 or 2; R4 is halogen, trifluoromethyl, alkyl, or alkoxy; n2 is 0, 1, 2, or 3; R2 is hydrogen or alkyl; and R3 is alkyl or alkoxy. Methods for making these compounds.