713139-25-4

Basic information

• Product Name: VCH-759
• Synonyms: VCH-759;sodiuM 3-(N-((1r,4r)-4-hydroxycyclohexyl)-4-MethylcyclohexanecarboxaMido)-5-phenylthiophene-2-carboxylate;VCH-759/VCH759;3-[(trans-4-Hydroxycyclohexyl)[(4-methylcyclohexyl)carbonyl]amino]-5-phenyl-2-thiophenecarboxylic acid;CKVYPTIWERNFSU-JNXHAIIESA-N
• CAS NO: 713139-25-4
• Molecular Formula: C25H31NO4S
• Molecular Weight: 441.58294
• Mol File: 713139-25-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: VCH-759(CAS DataBase Reference)
• NIST Chemistry Reference: VCH-759(713139-25-4)
• EPA Substance Registry System: VCH-759(713139-25-4)

Safety Data

• Hazardous Substances Data: 713139-25-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
VCH-759 is used as an anti-cancer agent for its ability to inhibit the activity of CDK4 and CDK6 enzymes, which are instrumental in cell cycle regulation and proliferation. This inhibition results in the suppression of cancer cell growth, particularly in hormone receptor-positive breast cancer.
Used in Cancer Research:
In the field of cancer research, VCH-759 is utilized to study the effects of CDK4 and CDK6 inhibition on cell cycle regulation and the potential for inducing apoptosis in cancer cells. This research is vital for understanding the compound's mechanism of action and its implications for cancer treatment.
Used in Clinical Trials:
VCH-759 is employed in clinical trials to evaluate its efficacy and safety as a targeted cancer therapy. These trials are essential for determining the potential of VCH-759 as a treatment option for patients with hormone receptor-positive breast cancer and other types of cancer where CDK4 and CDK6 inhibition may be beneficial.