71323-25-6 Usage
Description
1-(2-phenylethenyl)-1H-benzimidazole, also known as LY294002, is a synthetic chemical compound belonging to the benzimidazole family. It possesses potential anti-cancer and anti-inflammatory properties, making it a valuable tool for studying signaling pathways and a promising candidate for therapeutic development in cancer and inflammatory conditions.
Uses
Used in Pharmaceutical Research:
1-(2-phenylethenyl)-1H-benzimidazole is used as a research compound for studying the PI3K/AKT signaling pathway. Its ability to inhibit the activity of phosphatidylinositol 3-kinase (PI3K) makes it a valuable tool in understanding the role of this pathway in various diseases.
Used in Cancer Therapy Development:
In the pharmaceutical industry, 1-(2-phenylethenyl)-1H-benzimidazole is used as a potential therapeutic agent for the development of new cancer treatments. Its capacity to block PI3K signaling suggests that it could be a promising component in the fight against cancer.
Used in Inflammatory Disease Drug Development:
1-(2-phenylethenyl)-1H-benzimidazole is also used as a target for the development of drugs for inflammatory diseases. Its potential to modulate inflammatory responses makes it a valuable compound in the search for new treatments for conditions involving inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 71323-25-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,3,2 and 3 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 71323-25:
(7*7)+(6*1)+(5*3)+(4*2)+(3*3)+(2*2)+(1*5)=96
96 % 10 = 6
So 71323-25-6 is a valid CAS Registry Number.
71323-25-6Relevant articles and documents
An efficient N-arylation of heterocycles with aryl-, heteroaryl-, and vinylboronic acids catalyzed by copper fluorapatite
Kantam, Mannepalli Lakshmi,Venkanna, Gopaladasu Tirupati,Kumar, Kota Balaji Shiva,Subrahmanyam, Vura Bala
experimental part, p. 974 - 979 (2010/08/06)
N-Arylation of N-containing heterocycles, such as pyrazoles, imidazoles, and benzimidazoles with aryl-, heteroaryl-, and vinylboronic acids was efficiently carried out by copper fluorapatite (CuFAP) catalyst in MeOH at room temperature under base-free conditions. The N-arylated heterocycles were isolated in good-to-excellent yields.