71324-05-5Relevant articles and documents
Synthesis of s-indacene derivatives by double Robinson-type cyclopentene annulation
Zhang, Yawei,Christoffers, Jens
, p. 3061 - 3067 (2007)
Michael reactions of 2,5-dioxocyclohexane-1,4-dicarboxylates with methyl vinyl ketone yield bis-adducts that can be further cyclized in a Robinson-type annulation to give s-indacene derivatives as single diastereomers. The carboxylate functions of this scaffold can be deprotected and subsequently decarboxylated to yield tricyclic products with a central aromatic ring. Georg Thieme Verlag Stuttgart.