7134-41-0

Usage

Uses

Used in Organic Synthesis:
4-Mercaptobenzenesulfonic acid is used as a reagent in organic synthesis for its ability to participate in a wide range of chemical reactions, facilitating the creation of dyes, pharmaceuticals, and agrochemicals.
Used in Corrosion Inhibition:
In industrial applications, 4-mercaptobenzenesulfonic acid is used as a corrosion inhibitor. Its thiol group can form strong covalent bonds with metal surfaces, particularly with metals such as iron and steel, providing effective protection against corrosion.
Used in Electrochemistry:
4-Mercaptobenzenesulfonic acid has potential applications in electrochemistry due to its capacity to facilitate electron transfer processes, which is valuable in various electrochemical devices and systems.
Used as a Catalyst in Chemical Reactions:
Due to its ability to aid in electron transfer, 4-mercaptobenzenesulfonic acid is also utilized as a catalyst in chemical reactions, enhancing the rate and efficiency of these processes.

InChI:InChI=1/C6H6O3S2/c7-11(8,9)6-3-1-5(10)2-4-6/h1-4,10H,(H,7,8,9)

Upstream product

• 1161-11-1 4,4'-dithiobis(benzenesulphonic acid) 
• 111738-19-3 dianilinium 4,4'-dithiobis(benzenesulfonate) 
• 305-80-6 4-diazobenzenesulfonic acid 
• 121-57-3 4-aminobenzene sulfonic acid 

Downstream Products

• 111738-22-8 Sodium 4-((5-Methyl-2-oxo-1,3-dioxol-4-yl)methylthio)benzenesulfonate 
• 1161-11-1 4,4'-dithiobis(benzenesulphonic acid) 
• 856066-53-0 C₆H₅Sb(SC₆H₄-4-SO₃H)2 
• 856161-88-1 4-HOC₆H₄Sb(SC₆H₄-4-SO₃H)2 
• 856161-93-8 4-H₂NC₆H₄Sb(SC₆H₄-4-SO₃H)2*HCl 
• 856156-36-0 4-CH₃CONHC₆H₄Sb(SC₆H₄-4-SO₃H)2 
• 872792-06-8 C₃H₅N₆C₆H₄Sb(SC₆H₄SO₃H)2 

Relevant academic research and scientific papers

2-Oxo-1,3-dioxoles as specific substrates for measurement of arylesterase activity

Various 4-arylthiomethyl-2-oxo-1,3-dioxole derivatives IIIa-o were synthesized. Their hydrolysis rates by arylesterase (EC 3.1.1.2) and cholinesterase (EC 3.1.1.8) in human serum were evaluated. Some of them were not hydrolyzed by cholinesterase, but were

1,3-dioxol-2-one derivatives

A 1,3-dioxol-2-one derivative represented by the following formula (I) STR1 wherein R1 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, R2, R3, R4, R5 and R6 represent independently a hydrogen atom, a halogen atom, an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a nitro group, a carboxyl group, salts of the carboxyl group, a sulfo group and salts of the sulfo group, and a process for producing the 1,3-dioxol-2-one derivative. The compound is useful for measuring the activity of arylesterase.

Rate Constants and Equilibrium Constants for Thiol-Disulphide Interchange Reactions Involving Oxidized Glutathione

The rate of reduction of oxidized glutathione (GSSG) to glutathione (GSH) by thiolate (RS-) follows a Broensted relation in pKas of the conjugate thiols (RSH): βnuc ca. 0.5.This value is similar to that for reduction of Ellman's reagent: βnuc ca. 0.4 - 0.5.Analysis of a number of rate and equilibrium data, taken both from this work and from the literature, indicates that rate constants, k, for a range of thiolate-disulphide interchange reactions are correlated well by equations of the form log k = C + βnucpKanuc + βcpKac + βlgpKalg ( nuc = nucleophile, c = central, and lg = leaving group sulfur): eq 36 - 38 give representative values of the Broensted coefficients.The values of these Bronsted coefficients are not sharply defined by the available experimental data, although eq 36 - 38 provide useful kinetic models for rates of thiolate-disulfide interchange reactions.The uncertainty in these parameters is such that their detailed mechanistic interpretation is not worthwhile, but their qualitative interpretation - that all three sulphur atoms experience a significant effective negative charge in the transition state, but that the charge is concentrated on the terminal sulfurs - is justified.Equilibrium constants for reduction of GSSG using α,ω-dithiols have been measured.The reducing potential of the dithiol is strongly influenced by the size of the cyclic disulfide formed on its oxidation: the most strongly reducing dithiols are those which can form six-membered cyclic disulfides.Separate equilibrium constants for thiolate anion-disulphide interchange (KS-) and for thiol-disufide interchange (KSH) have been estimated from literature data: KS- is roughly proportional to 2ΔpKa is the difference between the pKas of the two thiols involved in the interchange.The contributions of thiol pKa values to the observed equilibrium constants for reduction of GSSG with α,ω-dithiols appear to be much smaller than those ascribable to the influence of structure on intramolecular ring formation.These equilibrium and rate constants are helpful in choosing dithiols for use as antioxidants in solutions containing proteines: dithiothreitol (DTT), 1,3-dimercapto-2-propanol (DMP), and 2-mercaptoethanol have especially useful properties.