71387-69-4Relevant academic research and scientific papers
Synthesis and anticonvulsant activity evaluation of 7-alkoxy-2, 4-dihydro-1H-benzo[b][1,2,4]triazolo[4,3-d][1,4]thiazin-1-ones in various murine experimental seizure models
Cao, Xu,Wang, Shi-Ben,Deng, Xian-Qing,Liu, Da-Chuan,Quan, Zhe-Shan
, p. 1829 - 1838 (2014/05/06)
A novel series of 7-alkoxy-2,4-dihydro-1H-benzo [b][1,2,4]triazolo[4,3-d] [1,4]-thiazin-1-ones have been synthesized and tested for their anticonvulsant activity using the maximal electroshock (MES) method. The majority of the compounds prepared were effe
Synthesis and anticonvulsant activity of some 7-alkoxy-2H-1,4-benzothiazin- 3(4H)-ones and 7-alkoxy-4H-[1,2,4]triazolo[4,3-d]benzo[b][1,4]thiazines
Zhang, Li-Qiu,Guan, Li-Ping,Wei, Cheng-Xi,Deng, Xian-Qing,Quan, Zhe-Shan
experimental part, p. 326 - 331 (2011/02/25)
A series of 7-alkoxy-2H-1,4-benzothiazin-3(4H)-ones and a new series of 7-alkoxy-4H-[1,2,4]triazolo[4,3-d]benzo[b][1,4]thiazine derivatives were synthesized using 5-methoxybenzo[d]thiazol-2-amine as starting material. The structures of the compounds were
Syntheses for 2-Hydroxy-2H-1,4-benzothiazin-3(4H)-one Derivatives as Thio Analogues of Natural Hemiacetals
Sicker, Dieter,Hartenstein, Holger,Hazard, Roland,Tallec, Andre
, p. 809 - 812 (2007/10/02)
Reductive cyclizations of methyl 2-(2-nitrophenylthio)acetate 2 by means of electrochemistry or by catalytic hydrogenation have been used as key steps in the syntheses of hemiacetals 2-hydroxy-2H-1,4-benzothiazin-3(4H)-one 10 and its 4-hydroxy derivative 9 representing thio analogues of allelo chemicals found in Gramineae and Acanthaceae.In contrast to its natural counterpart 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one hydroxamic acid 9 did not undergo degradation by extrusion of formic acid.
