71404-69-8

Basic information

• Product Name: (3aR,7S,7aS)-2-Oxo-7-phenylselanyl-octahydro-benzofuran-3-carboxylic acid methyl ester
• Synonyms: (3aR,7S,7aS)-2-Oxo-7-phenylselanyl-octahydro-benzofuran-3-carboxylic acid methyl ester
• CAS NO: 71404-69-8
• Molecular Weight: 353.277
• Mol File: 71404-69-8.mol

Chemical Properties

• CAS DataBase Reference: (3aR,7S,7aS)-2-Oxo-7-phenylselanyl-octahydro-benzofuran-3-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3aR,7S,7aS)-2-Oxo-7-phenylselanyl-octahydro-benzofuran-3-carboxylic acid methyl ester(71404-69-8)
• EPA Substance Registry System: (3aR,7S,7aS)-2-Oxo-7-phenylselanyl-octahydro-benzofuran-3-carboxylic acid methyl ester(71404-69-8)

Safety Data

• Hazardous Substances Data: 71404-69-8(Hazardous Substances Data)

Upstream product

• 5707-04-0 Phenylselenyl chloride 
• 2138-99-0 cyclohex-2-enyl-malonic acid 

Relevant articles and documents

ORGANOSELENIUM-INDUCED CYCLIZATIONS IN ORGANIC SYNTHESIS

A number of organoselenium reagents are introduced as efficient initiators of ring closures leading from unsaturated substrates to lactones, cyclic ethers, cyclic thioethers, N-heterocycles and carbocycles.These cyclizations often proceed with high ring selectivity and stereoselectivity and are accompained by the incorporation of the phenylseleno group (PheSe) into the final product.Methods are described for the effective removal of this group (PheSe) by oxidation or reduction achieving unsaturation or saturation.Finally the successful application of this Se-based methodology to the synthesis of stable and biologically active prostacyclins is outlined.Representative experimental procedures are included.