71404-73-4Relevant academic research and scientific papers
Stereoselective Selenolactonization by Superelectrophilic Benzeneselenenyl Triflate
Murata, Shizuaki,Suzuki, Toshiyasu
, p. 849 - 852 (2007/10/02)
Benzeneselenenyl triflate is prepared from benzeneselenenyl chloride and silver trifluoromethanesulfonate.It performs selenium-induced cyclization of β,γ-, γ,δ-, and δ,ε-unsaturated carboxylic acids.
ORGANOSELENIUM-INDUCED CYCLIZATIONS IN ORGANIC SYNTHESIS
Nicolaou, K.C.
, p. 4097 - 4109 (2007/10/02)
A number of organoselenium reagents are introduced as efficient initiators of ring closures leading from unsaturated substrates to lactones, cyclic ethers, cyclic thioethers, N-heterocycles and carbocycles.These cyclizations often proceed with high ring selectivity and stereoselectivity and are accompained by the incorporation of the phenylseleno group (PheSe) into the final product.Methods are described for the effective removal of this group (PheSe) by oxidation or reduction achieving unsaturation or saturation.Finally the successful application of this Se-based methodology to the synthesis of stable and biologically active prostacyclins is outlined.Representative experimental procedures are included.
