714201-62-4

Upstream product

• 185749-71-7 ethyl α-chloro-α-phenylseleno propionate 
• 714201-61-3 (6-methoxy-4,7-dimethyl-3,4-dihydro-naphthalen-2-yloxy)-trimethyl-silane 
• 130921-10-7 (±)-methoxy-4,7-dimethyl-3,4-dihydronaphthalen-1(2H)-one 
• 714201-59-9 4,7-dimethyl-6-methoxy-β-tetralone 
• 4513-72-8 4-methoxy-3-methylphenylacetyl chloride 

Relevant academic research and scientific papers

A new approach to (±)-heritonin. The preparation of β-tetralones from allylsilanes and acid chlorides

A new method for the preparation of 4-alkyl-β-tetralones is described, by reaction of arylacetic acid chlorides with allylsilanes. Employing β-tetralone 5, the synthesis of (±)-heritonine and (±)-epi-heritonine, natural piscicides isolated from Heritiera littoralis, was achieved in four steps and 22% overall yield. The key step of this synthesis involved the selenocarbenium ion-mediated elaboration of the butenolide ring of the natural product.