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(2E)-2-[cyclopropyl(3,4-dimethylphenyl)methylidene]hydrazinecarbothioamide is a hydrazinecarbothioamide derivative with a unique molecular structure featuring a cyclopropyl group attached to a (3,4-dimethylphenyl)methylidene group and a hydrazinecarbothioamide moiety. (2E)-2-[cyclopropyl(3,4-dimethylphenyl)methylidene]hydrazinecarbothioamide is a potential inhibitor of MDR 1 P-glycoprotein, a significant transporter protein in the human body, and exhibits antibacterial, antifungal, and antitumor properties, making it a promising candidate for pharmaceutical applications.

7145-46-2

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7145-46-2 Usage

Uses

Used in Pharmaceutical Industry:
(2E)-2-[cyclopropyl(3,4-dimethylphenyl)methylidene]hydrazinecarbothioamide is used as a potential therapeutic agent for its ability to inhibit MDR 1 P-glycoprotein, which can help overcome multidrug resistance in cancer treatment. Its antibacterial, antifungal, and antitumor properties also make it a candidate for the development of new drugs to combat various diseases and infections.
Used in Cancer Research:
In cancer research, (2E)-2-[cyclopropyl(3,4-dimethylphenyl)methylidene]hydrazinecarbothioamide is used as a potential antitumor agent due to its ability to target and inhibit MDR 1 P-glycoprotein, a protein often associated with resistance to chemotherapy drugs. This property allows the compound to enhance the effectiveness of conventional cancer treatments and improve patient outcomes.
Used in Antibacterial and Antifungal Applications:
(2E)-2-[cyclopropyl(3,4-dimethylphenyl)methylidene]hydrazinecarbothioamide is used as an antibacterial and antifungal agent, leveraging its inherent properties to combat bacterial and fungal infections. Its potential use in these applications can contribute to the development of new treatments for drug-resistant infections.
Used in Drug Resistance Studies:
In drug resistance studies, (2E)-2-[cyclopropyl(3,4-dimethylphenyl)methylidene]hydrazinecarbothioamide is used to investigate the mechanisms of multidrug resistance and develop strategies to overcome it. Understanding its interaction with MDR 1 P-glycoprotein can provide insights into the development of new drugs that can bypass resistance mechanisms in various diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 7145-46-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,4 and 5 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 7145-46:
(6*7)+(5*1)+(4*4)+(3*5)+(2*4)+(1*6)=92
92 % 10 = 2
So 7145-46-2 is a valid CAS Registry Number.

7145-46-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name [(Z)-[cyclopropyl-(3,4-dimethylphenyl)methylidene]amino]thiourea

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:7145-46-2 SDS

7145-46-2Upstream product

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