71458-60-1

Upstream product

• 938-09-0 2-chloroethyl phenyl sulfone 
• 699-12-7 2-(phenylthio)ethanol 
• 5535-49-9 2-Chloroethyl phenyl sulfide 
• 108-98-5 thiophenol 
• 71-43-2 benzene 
• 117078-03-2 2-ethylthioethyl phenyl sulphone 
• 1308834-02-7 2-(2-naphthylsulfanyl)ethyl phenyl sulfone 

Downstream Products

• 71458-65-6 Bis-(benzolsulfonyl-2-aethyl)-disulfid 
• 1242551-21-8 2-[2-(phenylsulfonyl)ethylthio]-N-(2-thienyl-methyl)-3-quinoline carboxamide 
• 1242435-94-4 2-[2-(benzenesulfonyl)ethylsulfanyl]-3-nitropyridine 
• 1242554-85-3 2-(2-(phenylsulfonyl)ethylthio)-6-(trifluoromethyl)quinoline-3-carboxylic acid 
• 1134169-15-5 2-[2-(benzenesulfonyl)ethylthio]-6-fluoro-N-(2-thienylmethyl)-nicotinamide 
• 1134169-11-1 2-[2-(benzenesulfonyl)ethylthio]-6-methyl-N-(2-thienylmethyl)-nicotinamide 

Relevant academic research and scientific papers

Pd-catalyzed reductive cleavage of alkyl aryl sulfides with triethylsilane that is accelerated by trialkylsilyl chloride

The palladium-catalyzed reductive cleavage of alkyl aryl sulfides to afford the corresponding arenes in high yield, which is both accelerated and exhibits increased functional group selectivity in the presence of TMSCl, is described. This ligand-free reaction features mild conditions, easy operation, use of readily available reagents, and high functional group selectivity.

SUBSTITUTED 3-AMINO-2-MERCAPTOQUINOLINES AS KCNQ2/3 MODULATORS

The invention relates to substituted 3-amino-2-mercaptoquinolines, to processes for their preparation, to medicaments containing these compounds and to the use of these compounds in the preparation of medicaments.