714953-86-3

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 17 carbon (C) atoms, 15 hydrogen (H) atoms, 1 fluorine (F) atom, 1 nitrogen (N) atom, and 1 oxygen (O) atom.

Explanation

A derivative is a compound that is structurally related to another compound, in this case, naphthol. The presence of an amino group and a 4-fluoro-phenyl-methyl group differentiates 1-[AMINO-(4-FLUORO-PHENYL)-METHYL]-NAPHTHALEN-2-OL from naphthol.

Explanation

The amino group (-NH2) is a functional group consisting of a nitrogen atom bonded to two hydrogen atoms. It is an essential component in many organic compounds and biological molecules.

Explanation

The 4-fluoro-phenyl-methyl group is a functional group consisting of a phenyl ring (a six-membered carbon ring with alternating single and double bonds) with a fluorine atom at the 4th position and a methyl group (-CH3) attached to the phenyl ring.

Explanation

Due to its unique structure and functional groups, 1-[AMINO-(4-FLUORO-PHENYL)-METHYL]-NAPHTHALEN-2-OL may be useful in the synthesis of various organic compounds and as a potential pharmaceutical intermediate in the development of new drugs.

Explanation

The presence of multiple functional groups in the molecule allows it to act as a building block for the synthesis of other organic compounds, which can be further modified or used in various applications.

Explanation

To fully understand the range of applications and potential uses for this chemical, additional research and analysis are necessary. This may involve studying its chemical reactivity, stability, and interactions with other compounds or biological systems.

Derivative of Naphthol

Yes

Amino Group

Present

4-Fluoro-Phenyl-Methyl Group

Present

Potential Applications

Organic Chemistry and Pharmaceuticals

Building Block

Synthesis of Organic Compounds

Pharmaceutical Intermediate

Development of New Drugs

Further Research and Analysis

Required

InChI:InChI=1/C17H14FNO/c18-13-8-5-12(6-9-13)17(19)16-14-4-2-1-3-11(14)7-10-15(16)20/h1-10,17,20H,19H2

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 135-19-3 β-naphthol 
• 1221591-23-6 C₂₄H₁₇F₂NO 

Relevant academic research and scientific papers

The isomeric structure of pentacoordinate chiral spirophosphoranes in solution by the combined use of NMR experiments and GIAO DFT calculations of NMR parameters

The interplay of NMR experiments and DFT calculations of NMR parameters is a reliable method for determining the relative configurations of pentacoordinate chiral spirophosphoranes bearing two six- or five-membered rings at the phosphorus atom in solution. The major product of the Betti based derivatives corresponds to the isomers with both substituents at chiral carbons being opposite to the P-H proton. The next populated product corresponds to the isomer with different chiralities at carbons. The least populated isomer is one with both substituents being at the same side of the heterocycle as the P-H bond.

High-performance liquid chromatographic enantioseparation of Betti base analogs on a newly developed isopropyl carbamate-cyclofructan6-based chiral stationary phase

The direct separation of the enantiomers of 1-(α-aminoarylmethyl)-2- naphthol, 1-(α-aminoalkyl)-2-naphthol, 2-(α-aminoarylmethyl)-1- naphthol analogs, and 2-(1-amino-2-methylpropyl)-1-naphthol) was performed on a newly developed chiral stationary phase containing isopropyl carbamate-cyclofructan6 as chiral selector, with n-heptane/alcohol/ trifluoroacetic acid as mobile phase. The effects of the mobile-phase composition, the nature and concentration of the alcoholic and acidic modifiers, and the structures of the analytes on the retention and resolution were investigated. In some cases, separations were carried out at constant mobile-phase compositions in the temperature range 5-40°C. Thermodynamic parameters and Tiso values were calculated from plots of ln k′ or ln α versus 1/T. -Δ(ΔH°) ranged from 2.8 to 3.2 kJ mol-1, -Δ(ΔS°) from 7.7 to 10.1 J mol-1 K-1, and -Δ(ΔG°) from 0.2 to 0.5 kJ mol-1. It was found that the enantioseparations were enthalpy driven. The sequence of elution of the stereoisomers determined in some cases was (R) (S).

Efficient synthesis of naphtho[1,2-e][1,3]oxazine derivatives via a chemoselective reaction with the aid of low-valent titanium reagent

A series of new naphtho[1,2-e][1,3]oxazine derivatives such as trans-1,3-diaryl-1H-naphtho[1,2-e][1,3]oxazine-2(3H)-carbonyl chloride, 1-aryl-2-benzyl-1,2- dihydronaphtho[1,2-e][1,3]oxazine-3-one, and trans-1,3-diaryl-1H-naphtho[1,2-e] [1,3]oxazine-2(3H)-

Stereoelectronic effects in ring-chain tautomerism of 1,3-diarylnaphth[1,2-e][1,3]oxazines and 3-alkyl-1-arylnaphth[1,2-e][1,3]oxazines

The disubstitution effects of X and Y in 1-(Y-phenyl)-3-(X-phenyl)-2,3-dihydro-1H-naphth[1,2-e][1,3]oxazines on the ring-chain tautomerism, the delocalization of the nitrogen lone pair (anomeric effect), and the 13C NMR chemical shifts were ana