714960-38-0Relevant academic research and scientific papers
6, 11-4-CARBON BRIDGED ERYTHROMYCIN DERIVATIVES
-
Page/Page column 48, (2010/02/06)
Novel 6,11-4-carbon bridged erythromycin derivatives and pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically-acceptable carrier are described. Also de
Allylation of Erythromycin Derivatives: Introduction of Allyl Substituents into Highly Hindered Alcohols
Stoner, Eric J.,Peterson, Matthew J.,Allen, Michael S.,DeMattei, John A.,Haight, Anthony R.,Leanna, M. Robert,Patel, Subhash R.,Plata, Daniel J.,Premchandran, Ramiya H.,Rasmussen, Michael
, p. 8847 - 8852 (2007/10/03)
Functionalized erythromycin 9-oxime derivatives are 6-O-allylated under mild conditions using substituted allyl tert-butyl carbonates under palladium(0) catalysis. This allylation works well where traditional ether-forming protocols function poorly. Allyl
