714962-19-3

Upstream product

• 184110-36-9 (2S,1'R/S)-2-(1'-Ethoxyethoxy)propanal 
• 150-76-5 4-methoxy-phenol 

Downstream Products

• 714962-21-7 Toluene-4-sulfonic acid (1S,3S,4R)-4-hydroxy-8-methoxy-1,3-dimethyl-isochroman-5-yl ester 
• 758695-37-3 Toluene-4-sulfonic acid 2-((2S,4R,5S)-2,5-dimethyl-[1,3]dioxolan-4-yl)-4-methoxy-phenyl ester 
• 162285-92-9 (1S,3S,4R)-3,4-Dihydro-4,5-dihydroxy-1,3-dimethyl-8-methoxy-2-benzopyran 

Relevant academic research and scientific papers

Short, convergent, stereoselective syntheses of enantiopure 2-benzopyran-5,8-quinones related to the aphid insect pigments, the protoaphins

The enantiopure (1S,3S,4R)-, (1R,3S,4S)- and (1S,3S,4S)-3,4-dihydro-1,3- dimethyl-4-hydroxy-2-benzopyrans 16, 25 and 26 are prepared in two related reaction sequences, each in eight steps and good overall yield. The starting materials are 4-methoxyphenol