714972-00-6 Usage
Uses
Used in Pharmaceutical Industry:
2-Amino-5-(trifluoromethyl)oxazole is utilized as a key intermediate in the synthesis of pharmaceutical drugs due to its unique structure and properties. Its presence in drug molecules can enhance their pharmacological activity, selectivity, and bioavailability, making it a valuable component in drug discovery and development processes.
Used in Medicinal Chemistry Research:
As a heterocyclic compound, 2-Amino-5-(trifluoromethyl)oxazole serves as a building block in the synthesis of diverse organic compounds with potential applications in medicinal chemistry. Its incorporation into various molecular frameworks can lead to the discovery of new therapeutic agents with improved efficacy and selectivity against specific biological targets.
Used in Chemical Synthesis:
2-Amino-5-(trifluoromethyl)oxazole is employed as a versatile synthetic building block in the preparation of a wide range of organic compounds. Its reactivity and functional group compatibility make it suitable for various synthetic transformations, enabling the development of novel chemical entities with potential applications in various fields, including materials science, agrochemistry, and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 714972-00-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,1,4,9,7 and 2 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 714972-00:
(8*7)+(7*1)+(6*4)+(5*9)+(4*7)+(3*2)+(2*0)+(1*0)=166
166 % 10 = 6
So 714972-00-6 is a valid CAS Registry Number.
InChI:InChI=1/C4H3F3N2O/c5-4(6,7)2-1-9-3(8)10-2/h1H,(H2,8,9)
714972-00-6Relevant academic research and scientific papers
Fluorinated 9H-xanthene-9-carboxylic acid oxazol-2-yl-amides as potent, orally available mGlu1 receptor enhancers
Vieira, Eric,Huwyler, Joerg,Jolidon, Synese,Knoflach, Frederic,Mutel, Vincent,Wichmann, Juergen
scheme or table, p. 1666 - 1669 (2009/11/30)
Small molecule mGluR1 enhancers, which are 9H-xanthene-9-carboxylic acid [1,2,4]oxadiazol-3-yl- and (2H-tetrazol-5-yl)-amides, have been previously reported. Fluorinated 9H-xanthene-9-carboxylic acid oxazol-2-yl-amides with improved pharmacokinetic proper
Oxazoles as mGluR 1 enhancers
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Page/Page column 6, (2010/02/07)
The invention relates to carboxamide derivatives as defined in the specification and claims, to a process for their preparation, to pharmaceutical compositions comprising them and to their use as mGluR1 enhancers in the treatment and prevention of neurological disorders and diseases, such as Alzheimer's disease and dementia.
