71512-25-9

Upstream product

• 50397-64-3 methyl 2-(p-tolylsulfonyl)acetate 
• 106-95-6 allyl bromide 
• 35466-83-2 allyl methyl carbonate 
• 90083-98-0 sodium methyl(α-p-toluenesulfonyl)acetate 
• 455-16-3 p-toluenesulfonyl fluoride 

Downstream Products

• 851762-26-0 2-allyl-4-ethyl-2-(toluene-4-sulfonyl)-pent-4-enoic acid methyl ester 
• 851762-27-1 2-allyl-4-phenyl-2-(toluene-4-sulfonyl)-pent-4-enoic acid methyl ester 
• 851762-28-2 2-Allyl-4-methylene-2-(toluene-4-sulfonyl)-dodecanoic acid methyl ester 
• 112778-56-0 2-Allyl-2-(toluene-4-sulfonyl)-pent-4-enoic acid methyl ester 
• 851762-39-5 4-oxo-2-(2-oxo-ethyl)-4-phenyl-2-(toluene-4-sulfonyl)-butyric acid methyl ester 
• 1531-16-4 methyl 2-ethylpyridine-4-carboxylate 
• 4634-14-4 2-phenylisonicotinic acid methyl ester 

Relevant academic research and scientific papers

A [3,3]-sigmatropic process catalysed by acetate. The decarboxylative Claisen rearrangement

Allylic tosylacetates and tosylmalonates undergo acetate-catalysed decarboxylative Claisen rearrangement in the presence of N,O-bis(trimethylsilyl) acetamide. The homoallylic sulfones formed in these transformations correspond to the products of regiospecific allylation of sulfone-stabilised carbanions. A mechanistic rationale is proposed.

Sulfone-mediated synthesis of polysubstituted pyridines

Base-mediated and/or palladium(0)-catalysed bis(allylation) of alkyl 2-(tolylsulfonyl)acetates gives 1,6-dienes, which upon ozonolytic cleavage of the double bonds and ammonolysis give 2,6-disubstituted pyridine-4-carboxylic esters. Decarboxylation of one

Decarboxylative Claisen rearrangement reactions of allylic tosylmalonate esters

(Chemical Equation Presented) Two different combinations of silylating agent and base are used for one-pot [3,3]-sigmatropic rearrangement- decarboxylation reactions of tosylmalonic mono(allylic) esters under mild conditions, providing the products of formal regiospecific allylation of methyl tosylacetate at the more substituted allylic terminus.

Titanium Oxide-Supported Carbonylmolybdenum Catalyst in Liquid Phase: Application to Allylic Alkylation of Methyl p-Tolylsulfonylacetate

Titanium oxide-supported carbonylmolybdenum catalyst was applied to selective monoallylation of methyl p-tolylsulfonylacetate using allylic acetates or carbonates in refluxing dioxane.This reaction required both 2,2'-bipyridyl as a ligind and sodium hydride as a base for preparation of the salt of methyl p-tolylsulfonylacetate.

Hexacarbonylmolybdenum(0)-Catalyzed Reaction of Allylic Carbonates with Arylsulfonyl-Stabilized Carbanions

p-Tolylsulfonylacetonitrile reacted with allylic carbonates in the presence of a catalytic amount of hexacarbonylmolybdenum(0) to give monoallylated derivatives.Using sodium hydride as a base, methyl p-tolylsulfonylacetate reacted with those to give mixtu