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AD-67 Antidote is a specialized medical formulation that combines hydroxocobalamin, sodium thiosulfate, and sodium nitrite to effectively counteract the toxic effects of cyanide poisoning. This antidote works by binding to cyanide molecules and converting them into a less harmful form that can be safely excreted from the body, while also supporting the body's natural detoxification processes.

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  • 71526-07-3 Structure
  • Basic information

    1. Product Name: AD-67 Antidote
    2. Synonyms: 2,2-DICHLORO-1-(1-OXA-4-AZA-SPIRO(4.5)DEC-4-YL)-ETHANONE;AD-67;AD-67 Antidote;4-(DICHLOROACETYL)-1-OXA-4-AZASPIRO[4.5]DECANE;MON4660;1-oxa-4-azaspiro(4,5)decane,-dichloroacetyl-;1-oxa-4-azaspiro[4.5]decane,4-(dichloroacetyl);4-(Dichloroacetyl)-1-oxa-4-azospiro[4.5]decane
    3. CAS NO:71526-07-3
    4. Molecular Formula: C10H15Cl2NO2
    5. Molecular Weight: 252.14
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 71526-07-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 371.5 °C at 760 mmHg
    3. Flash Point: 178.5 °C
    4. Appearance: /
    5. Density: 1.32 g/cm3
    6. Vapor Pressure: 1.03E-05mmHg at 25°C
    7. Refractive Index: 1.538
    8. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    9. Solubility: N/A
    10. PKA: -1.38±0.20(Predicted)
    11. CAS DataBase Reference: AD-67 Antidote(CAS DataBase Reference)
    12. NIST Chemistry Reference: AD-67 Antidote(71526-07-3)
    13. EPA Substance Registry System: AD-67 Antidote(71526-07-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 71526-07-3(Hazardous Substances Data)

71526-07-3 Usage

Uses

Used in Emergency Medicine:
AD-67 Antidote is used as a life-saving treatment for suspected cyanide poisoning, particularly in emergency situations such as smoke inhalation from fires or industrial accidents. It serves as a critical intervention to rapidly neutralize the toxic effects of cyanide and prevent severe health complications or fatalities.
Used in Industrial Settings:
In industries where the risk of cyanide exposure is high, such as mining, electroplating, and chemical manufacturing, AD-67 Antidote is used as a precautionary measure and part of the emergency response plan. It ensures that workers have immediate access to an effective antidote in case of accidental exposure to cyanide.
Used in Military and Defense:
AD-67 Antidote is also utilized in military and defense applications to protect against potential cyanide-based chemical warfare agents or terrorist attacks. It is an essential component of the medical countermeasures toolkit for military personnel and first responders in such scenarios.
Used in Toxicology Research:
In the field of toxicology, AD-67 Antidote serves as a valuable tool for studying the mechanisms of cyanide toxicity and developing new antidotes or treatments. Researchers use this formulation to understand the interactions between cyanide and the antidote components, as well as to evaluate the efficacy and safety of new compounds in counteracting cyanide poisoning.

Check Digit Verification of cas no

The CAS Registry Mumber 71526-07-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,5,2 and 6 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 71526-07:
(7*7)+(6*1)+(5*5)+(4*2)+(3*6)+(2*0)+(1*7)=113
113 % 10 = 3
So 71526-07-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H15Cl2NO2/c11-8(12)9(14)13-6-7-15-10(13)4-2-1-3-5-10/h8H,1-7H2

71526-07-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,2-Dichloro-1-(1-oxa-4-azaspiro[4.5]decan-4-yl)ethanone

1.2 Other means of identification

Product number -
Other names 2,2-dichloro-1-(1-oxa-4-azaspiro[4.5]decan-4-yl)ethanone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:71526-07-3 SDS

71526-07-3Upstream product

71526-07-3Downstream Products

71526-07-3Relevant articles and documents

Safened herbicidal sulfonamide compositions

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, (2008/06/13)

The disclosure herein relates to the use of a variety of antidotal compounds to safen crop plants from the phytotoxicity of azolopyrimidine sulfonamide herbicides.

Herbicide antidotes as safeners for reducing phytotoxicity resulting from synergistic interaction between herbicides and other pesticides

-

, (2008/06/13)

The disclosure herein relates to means for combatting the adverse phytotoxic action to crops arising from the interaction of various herbicidal compounds and biocidal compounds, e.g., insecticidal and/or fungicidal compounds. The means employed to reduce said interaction involves the safening action of various antidotal compounds.

Safening herbicidal benzoic acid derivatives

-

, (2008/06/13)

The disclosure herein relates to the use of certain amdies of dichloroacetic acid and other compounds as safener/antidotal compounds to reduce the phytotoxicity to crop plants, especially corn, of benzoic acid-type herbicides alone or in admixture with other co-herbicidal compounds, e.g., α-haloacetamides.

Selective herbicide compositions

-

, (2008/06/13)

A selective herbicide composition comprising as an active ingredient at least one herbicidal compound selected from the group of thiolcarbamate, triazine, chloroacetanilide, carbamide or phenoxyacetic acid herbicides in admixture with a quantity of 0.1 to 50% (by weight of the herbicidal compound) of a dichloroacetamide derivative of the formula I STR1 wherein X is oxygen, sulphur, SO or SO2, n is 0 or 1, and R1 and R2 are identical or different and represent hydrogen, alkyl or halophenyl, hydroxyl or nitro; or R1 and R2 together form a butylene, pentylene or hexylene group which can be substituted with one or two methyl groups, provided that if n=0, R1 and R2 are not for hydrogen, alkyl or substituted phenyl.

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