71555-91-4Relevant academic research and scientific papers
Photochemical ring opening of 1-arylpyrimidin-2(1H)-ones
Nishio, Takehiko,Katahira, Katsuhiro,Omote, Yoshimori
, p. 943 - 946 (2007/10/02)
The photochemical reactions of 1-arylpyrimidin-2(1H)-ones have been examined. Irradiation of the 1-arylpyrimidin-2(1H)-ones (3a-f) in benzene-methanol gave 1-alkoxycarbonylamino-3-aryliminoprop-1-enes (4), (6), and (7), which were hydrolysed to give the corresponding 3-alkoxycarbonylaminoprop- 2-enal (5), in 45-55% yield. The formation of the N-arylimine products (4), (6), and (7) was presumed to arise from an unstable isocyanate intermediate (8) formed initially by Type I cleavage of the 1-arylpyrimidin-2(1H)-one (3).
