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CAS

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71567-77-6

Glicentin, also known as Glucagon-like peptide-1 (GLP-1), is a gastrointestinal hormone that is a 30-amino acid peptide generated by the intestinal epithelial endocrine L-cells. It is mapped to human chromosome 2q24 and plays a crucial role in various physiological processes.

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  • 71567-77-6 Structure

  • Basic information

    1. Product Name: glicentin
    2. Synonyms: glicentin;Anti-Glucagon antibody produced in rabbit;Glucagon-like peptide 1(GLP-1)
    3. CAS NO:71567-77-6
    4. Molecular Formula: C21H18O6
    5. Molecular Weight: 366.36402
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 71567-77-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 553.7°C at 760 mmHg
    3. Flash Point: 244.4°C
    4. Appearance: /
    5. Density: 1.41g/cm3
    6. Vapor Pressure: 2.65E-12mmHg at 25°C
    7. Refractive Index: 1.654
    8. Storage Temp.: -20°C
    9. Solubility: N/A
    10. CAS DataBase Reference: glicentin(CAS DataBase Reference)
    11. NIST Chemistry Reference: glicentin(71567-77-6)
    12. EPA Substance Registry System: glicentin(71567-77-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 71567-77-6(Hazardous Substances Data)

71567-77-6 Usage

Uses

Used in Immunohistochemistry:
Glicentin is used as a biomarker in immunohistochemistry for the identification and localization of L-cells within the gastrointestinal tract. This application helps researchers understand the distribution and function of these cells in health and disease.
Used in Pharmaceutical Research:
Glicentin is used as a target for the development of new drugs and therapies related to glucose homeostasis and appetite regulation. Its role in the regulation of blood glucose levels and its potential to stimulate insulin secretion make it a promising candidate for the treatment of type 2 diabetes and obesity.
Used in Diagnostic Applications:
Glicentin can be used as a diagnostic marker to assess the functionality of the gastrointestinal system and the presence of L-cells. This can help in the early detection of gastrointestinal disorders and guide appropriate treatment strategies.
Used in Nutritional Research:
Glicentin is used as a research tool to study the effects of various nutrients and dietary patterns on gastrointestinal hormone secretion. This can help in the development of personalized nutrition plans and the design of functional foods with potential health benefits.
Used in Endocrinology:
Glicentin is used as a research subject in endocrinology to understand its role in the regulation of glucose metabolism and energy balance. This knowledge can contribute to the development of novel therapeutic approaches for metabolic disorders and the optimization of existing treatments.

Biochem/physiol Actions

Glucagon-like peptide-1 (GLP-1) increases glucose-dependent insulin secretion and terminates the liberation of glucagon. It acts as a physiological regulator of appetite and food intake. GLP-1 also helps to prevent the gastrointestinal movement and secretion.

Check Digit Verification of cas no

The CAS Registry Mumber 71567-77-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,5,6 and 7 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 71567-77:
(7*7)+(6*1)+(5*5)+(4*6)+(3*7)+(2*7)+(1*7)=146
146 % 10 = 6
So 71567-77-6 is a valid CAS Registry Number.
InChI:InChI=1/C21H18O6/c1-23-15-6-4-11-7-13-9-25-21(22)19(13)17(18(11)20(15)24-2)12-3-5-14-16(8-12)27-10-26-14/h3-6,8,17H,7,9-10H2,1-2H3/t17-/m1/s1

71567-77-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (4R)-4-(1,3-benzodioxol-5-yl)-5,6-dimethoxy-4,9-dihydro-1H-benzo[f][2]benzofuran-3-one

1.2 Other means of identification

Product number -
Other names Glicentine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:71567-77-6 SDS

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