71578-43-3Relevant articles and documents
ETUDE DE LA RACEMISATION INDUITE PAR LA DMAP DANS LES REACTIONS DE COUPLAGE PEPTIDIQUE
Gamet, Jean-Paul,Jacquier, Robert,Verducci, Jean
, p. 1995 - 2002 (1984)
The scope and limitation for the use of 4-dimethyalmino pyridine (DMAP) as additive to carbodiimides in peptide synthesis are studied and compared with the results obtained with N-hydroxybenzotriazole (HOBt).The activation of N-acylated aminoacids by the
THE DEPENDENCE OF ASYMMETRIC INDUCTION ON SOLVENT POLARITY AND TEMPERATURE IN PEPTIDE SYNTHESIS
Benoiton, N. Leo,Kuroda, K.,Chen, F. M. F.
, p. 3361 - 3364 (2007/10/02)
When a racemic 2,4-dialkyl-5(4H)-oxazolone reacts with an L-amino acid ester, the D-L epimer is formed in excess in apolar solvents and the L-L epimer is formed in excess in polar solvents, the proportion of L-L isomer increasing with decreasing temperature.