71579-64-1Relevant academic research and scientific papers
Asymmetric Oxidation of Thioethers. Enantioselective Synthesis of β-Hydroxysulfoxides by Direct Oxidation
Conte, Valeria,Furia, Fulvio Di,Licini, Giulia,Modena, Giorgio
, p. 4859 - 4862 (2007/10/02)
S-methyl β-hydroxysulfoxides of fairly high optical purity (up to 80percent) may be prepared by direct asymmetric oxidation of acetylated or silylated S-methyl β-hydroxysulfides and subsequent deprotection.The upgrading of t
STEREOCHEMISTRY OF ORGANIC SULPHUR COMPOUNDS. Part 13. CONFIGURATIONAL ASSIGNMENT OF DIASTEREOISOMERS OF 2-METHYLSULPHINYL-1,2-DIPHENYLETHANOL AND THEIR O-METHYL AND O-ACETYL DERIVATIVES
Brunet, E.,Ruano, J. L. Garcia,Martinez, M. C.,Rodrigez, J. H.,Alcudia, F.
, p. 2023 - 2034 (2007/10/02)
The synthesis, isolation and conformational analysis of the diastereomeric 2-methylsulphinyl-1,2-diphenylethanol and its O-methyl and O-acetyl derivatives are reported.Chemical correlations and the study of the influence of solvent polarity changes on the coupling constants have permitted the configurational assignment.Lanthanide shift reagents have been used also to this effect.The role of hydrogen bonding in the hydroxysulphoxides has been evaluated in diluted solutions by IR and NMR spectroscopy.A donor-acceptor interaction between oxygen and sulphur has been invoked to explain the differences in conformational behaviuor between epimeric sulphoxides at sulphur atom.
