7159-14-0Relevant articles and documents
VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS
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Page/Page column 20, (2008/06/13)
Pyrimidine ethers and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
New substituted 1,4-benzoxazine derivatives with potential intracellular calcium activity
Bourlot, Anne-Sophie,Sánchez, Isabel,Dureng, Georges,Guillaumet, Gérald,Massingham, Roy,Monteil, André,Winslow, Eileen,Pujol, M. Dolors,Mérour, Jean-Yves
, p. 3142 - 3158 (2007/10/03)
Substituted 1,4-benzoxazines bearing an amino side chain at the 2- position were prepared and were found to have a moderate activity on intracellular calcium. Of the compounds studied it was found that those which possess a homoveratrylamino moiety exhibi
Synthesis of a benzodioxinic analog of 8-methoxypsoralen
Besson, Thierry,Ruiz, Nicolas,Coudert, Gerard,Guillaumet, Gerald
, p. 3197 - 3204 (2007/10/02)
A synthesis of a benzodioxinic analog of 8-methyoxypsoralen (8-MOP), in 12 steps from the commercially available 6-acetyl-2,3-dihydro-1,4-benzodioxin is described.
Synthese et proprietes biologiques photoinduites de dioxinnocoumarines lineaires
Guillaumet, Gerald,Hretani, Mohamed,Coudert, Gerard,Averbeck, Dietrich,Averbeck, Simone
, p. 45 - 51 (2007/10/02)
Synthesis and photoinduced biological properties of linear dioxinocoumarins.Several dioxinocoumarins with a substituted or unsubstituted coumarin moiety were synthesized from commercially available 6-amino-1,4-benzodioxan.Qualitative assays on the photoinduced inhibition of growth in the yeast Saccharomyces cerevisiae indicate that two dioxinocoumarins are photobiologically active. The 5H- benzopyranobenzodioxin-5-one 1d is more active than angelicin but less active than 8-MOP.The 9-methyl-7H-pyranobenzodioxin-7-one 1c is slightly less active than angelicin.