71595-18-1 Usage
Uses
Used in Pharmaceutical Industry:
(7-BROMOQUINOLIN-4-YL)PROPYLAMINE is used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. Its unique structure allows it to be a key component in the development of new drugs and therapeutic agents.
Used in Medicinal Chemistry:
(7-BROMOQUINOLIN-4-YL)PROPYLAMINE is utilized in medicinal chemistry for its potential applications in drug development. Its quinoline core and bromine atom at the 7th position contribute to its unique properties, making it a valuable compound for designing and synthesizing new pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 71595-18-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,5,9 and 5 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 71595-18:
(7*7)+(6*1)+(5*5)+(4*9)+(3*5)+(2*1)+(1*8)=141
141 % 10 = 1
So 71595-18-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H13BrN2/c1-2-6-14-11-5-7-15-12-8-9(13)3-4-10(11)12/h3-5,7-8H,2,6H2,1H3,(H,14,15)
71595-18-1Relevant academic research and scientific papers
Synthese de modeles du complexe chloroquine-ADN
Bolte, Jean,Demuynck, Colette,Lhomme, Jean
, p. 316 - 320 (2007/10/02)
Chloroquine is an antimalarial drug which inhibits the DNA and RNA polymerase reactions and which has been shown to bind reversibly with nucleic acids.The "intercalation" mode of binding has been proposed by which the 4-amino-7-chloroquinoline ring of the drug interacts with the nucleotide bases of the polymer.As an approach to the problem of the nature of the forces responsible for these ring-ring stacking interactions, we have prepared models in which the aromatic nucleus of the drug is linked to the nucleotide bases by a trimethylene chain.We describe here the preparation of different models in which the nucleotide bases are adenine and guanine linked through their N-7 atom, and the 4-aminoquinolines bear H or Br at the C-7 position.Comparable compounds in which quinoline is methylated on N-1 are also described.
