716324-25-3Relevant articles and documents
Rhodium-Catalyzed Regioselective Formal Hydroacylation of Vinyl Epoxides toward Esters Involving β-Carbon Cleavage
Chang, Zhi-Xin,Gong, Fei-Yuan,Wang, Xiaodan,Zhang, Tongbo,Han, Junfen,Li, Hong-Shuang
supporting information, p. 6084 - 6089 (2021/08/16)
Herein we disclose the first example of the formal hydroacylation reactions of vinyl epoxides with chelating aldehydes enabled by rhodium catalysis for the efficient construction of functionalized esters. Detailed investigations of the mechanistic pathway reveal that the presence of a 2-vinyl group is essential in contributing to the success of this regioselective reaction, which might proceed through β-carbon cleavage as the key procedure.
Catalytic ring expansion of vinyl oxetanes: Asymmetric synthesis of dihydropyrans using chiral counterion catalysis
Guo, Boying,Schwarzwalder, Gregg,Njardarson, Jon T.
supporting information; experimental part, p. 5675 - 5678 (2012/07/03)
Acid Showdown! The first catalytic ring expansion of vinyl oxetanes to 3,6-dihydro-2H-pyrans is described. Copper(II) triflate emerged as the best catalyst for this new transformation, which has broad scope as demonstrated by the eighteen examples included. The symmetric vinyl oxetane substrate can be asymmetrically desymmetrized when using either chiral Lewis or Bronsted acids as catalysts. Copyright
