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2-(3-ethyl-ureido)-5-[4-(3-nitro-phenyl)-piperazin-1-yl]-5-oxo-pentanoic acid tert-butyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

716377-48-9

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716377-48-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 716377-48-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,1,6,3,7 and 7 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 716377-48:
(8*7)+(7*1)+(6*6)+(5*3)+(4*7)+(3*7)+(2*4)+(1*8)=179
179 % 10 = 9
So 716377-48-9 is a valid CAS Registry Number.

716377-48-9Relevant academic research and scientific papers

Discovery of a potent and selective αvβ3 integrin antagonist with strong inhibitory activity against neointima formation in rat balloon injury model

Iwama, Seiji,Kitano, Tomoko,Fukuya, Fumiyo,Honda, Yayoi,Sato, Yuji,Notake, Mitsue,Morie, Toshiya

, p. 2567 - 2570 (2007/10/03)

A new series of phenylpiperazine-based derivatives with strong antagonistic activity for αvβ3 integrin were synthesized. Of these derivatives, the fluorine-substituted compound 8 showed strong inhibitory activity and high selectivity for αvβ 3 integrin receptor (IC50=0.055nM). In vivo evaluation of the antistenotic effects of 8 indicated that this compound significantly inhibits neointima formation in rat balloon injury model.

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