71643-02-2

Upstream product

• 371-41-5 4-Fluorophenol 
• 71643-58-8 4-fluoro-2,6-bis(hydroxymethyl)phenol 
• 50-00-0 formaldehyd 

Downstream Products

• 78563-27-6 Acetic acid 2,6-bis-(2-acetoxy-3-acetyl-5-fluoro-benzyl)-4-fluoro-phenyl ester 
• 78563-15-2 1-acetoxy-2,6-bis(2'-acetoxy-5'-fluorobenzoyl)-4-fluorobenzene 
• 78615-24-4 2,6-bis(3-acetyl-5-fluoro-2-hydroxy-benzoyl)-4-fluorophenol 
• 71643-19-1 2,6-bis(2-hydroxy-3-iodo-5-fluorobenzyl)-4-fluorophenol 
• 71643-04-4 2,6-bis(2-hydroxy-3-bromo-5-fluorobenzyl)-4-fluorophenol 

Relevant academic research and scientific papers

Solvent-free synthesis of trisphenols as starting precursors for the synthesis of calix[4]arenes using sulfonated multi-walled carbon nanotubes

The condensation of phenol derivatives (12 substrates) with 2,6-bis(hydroxymethyl)phenols (BMP) (6 examples) is reported using sulfonated multi-walled carbon nanotubes (SO3H@MWCNTs) under solvent-free conditions as starting precursors for the synthesis of macrocyclic molecules of calix[4]arenes. The new protocol provides a series of trisphenol derivatives (21 examples) in high yields (up to 94%) and relatively short reaction times (15-120 min). Also, direct synthesis of calix[4]arenes from different trisphenols by use of the catalyst was reported (5 examples). Furthermore, the synthesized calix[4]arene was obtained using a one-pot method from simple and easily available starting materials such as p-cresol for the synthesis of 5,11,17,23-tetramethylcalix[4]arene-25,26,27,28-tetraol. Also, in this process SO3H@MWCNTs can be reused for seven runs with almost consistent efficiency and can be recovered by easy filtration.

An efficient synthetic approach to substituted trisphenols (phloroglucide analogues) using tungstosilicic acid in water

Tungstosilicic acid was found to be an efficient catalyst for the synthesis of trisphenols using the reaction of 2,6-bis(hydroxymethyl)phenols with phenols in an aqueous medium. The catalytic reactivity of tungstosilicic acid in boiling water was examined with a series of substrates, demonstrating that this catalyst is reactive in the presence of a variety of functionalities. Georg Thieme Verlag Stuttgart. New York.

The Synthesis of Polyfunctional Aromatic Ring Systems. Structural Analogues of Phloroglucides, Aranciamycin, Cryptosporin and Terramycin

The synthesis of the title compounds is described.Some of the compounds prepared were found to be active against a number of pathogenic microorganisms in vitro.

Treatment of animals with 2,6-bis(2-hydroxybenzyl)phenols to eradicate trematodes

A process for killing internal parasites of warm blooded animals which process comprises treating the infected animal with an effective amount of a composition comprising as active ingredient a compound of the general formula I: STR1 wherein R1