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Ethyl 2,2-diethoxyacetimidate is a versatile chemical compound utilized in organic synthesis, characterized by its imidate functional group with two ethoxy groups attached. Derived from ethylamine and diethyl carbonate, this reagent is recognized for its mild reaction conditions and high selectivity, making it an indispensable tool in the preparation of complex organic molecules, including esters, amides, β-lactams, and other nitrogen-containing heterocycles.

71648-28-7

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71648-28-7 Usage

Uses

Used in Organic Synthesis:
Ethyl 2,2-diethoxyacetimidate serves as a reagent for the preparation of esters and amides, facilitating the formation of these compounds under mild conditions with high selectivity.
Used as a Protecting Group in Sensitive Carbonyl Compounds:
In the synthesis of complex organic molecules, ethyl 2,2-diethoxyacetimidate is employed as a protecting group for sensitive carbonyl compounds, preventing unwanted side reactions and ensuring the desired product formation.
Used in the Formation of β-Lactams and Nitrogen-Containing Heterocycles:
ethyl 2,2-diethoxyacetimidate plays a crucial role in the synthesis of β-lactams, which are the core structures of penicillin and other antibiotics, as well as other nitrogen-containing heterocycles, contributing to the development of novel pharmaceuticals and bioactive molecules.
Used in Pharmaceutical Industry:
Ethyl 2,2-diethoxyacetimidate is used as a key intermediate in the synthesis of various pharmaceutical compounds, particularly in the preparation of antibiotics and other bioactive molecules, due to its ability to form stable intermediates and protect sensitive functional groups during the synthesis process.
Used in Research and Development:
In academic and industrial research settings, ethyl 2,2-diethoxyacetimidate is utilized for the exploration of new synthetic pathways and the development of innovative methodologies in organic chemistry, further expanding the scope of chemical synthesis and its applications.

Check Digit Verification of cas no

The CAS Registry Mumber 71648-28-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,6,4 and 8 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 71648-28:
(7*7)+(6*1)+(5*6)+(4*4)+(3*8)+(2*2)+(1*8)=137
137 % 10 = 7
So 71648-28-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H17NO3/c1-4-10-7(9)8(11-5-2)12-6-3/h8-9H,4-6H2,1-3H3/b9-7-

71648-28-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 2,2-diethoxyethanimidate

1.2 Other means of identification

Product number -
Other names 2,2-Diaethoxy-acetimidsaeure-aethylester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:71648-28-7 SDS

71648-28-7Relevant academic research and scientific papers

Synthesis, guest binding, and metal coordination of functionalized self-folding deep cavitands

Mettry, Magi,Moehlig, Melissa P.,Hooley, Richard J.

supporting information, p. 1497 - 1500 (2015/03/30)

A simple method to introduce donor functions to the upper rim of self-folding benzimidazole-based deep cavitands is described. The upper rim donors allow controlled noncovalent binding of suitably sized guest species via both self-complementary hydrogen bonding and space-filling interactions, and metal-mediated self-folding is possible if bidentate coordinators are incorporated.

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