71681-34-0Relevant academic research and scientific papers
Substituted pyrazole derivatives condensed with six-membered heterocyclic rings
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Page column 40, (2010/02/07)
The present invention relates to novel substituted pyrazole derivatives of the general formula (I) in which R1, R2, R3and A are each as defined, and to processes for their preparation and to their use as medicaments, in pa
ON THE REACTIVITY OF HALO-1,3-AZOLES AND RELATED COMPOUNDS TOWARD AROMATIC SN2 SUBSTITUTION
Yamanaka, Hiroshi,Ohba, Setsuya,Sakamoto, Takao
, p. 1115 - 1127 (2007/10/02)
Nucleophilic addition-elimination reactions of 2-methylsulfonyl-1,3-azoles with active methylene compounds were investigated in order to compare the reactivity of substrates.The order of oxazole > thiazole >> N-methylimidazole in the reactivity was exhibited clearly.Furthermore, in oxazole and thiazole series, the predominant reactivity of the 2-position over the 4- and 5-positions was indicated on the reaction with the carbanions generated from active methylene compounds.
