71692-31-4Relevant academic research and scientific papers
Synthesis, structure-activity relationships and preliminary mechanism study of N-benzylideneaniline derivatives as potential TLR2 inhibitors
Cai, Shaoyi,Zhu, Gengzheng,Cen, Xiaohong,Bi, Jingjie,Zhang, Jingru,Tang, Xiaoshan,Chen, Kun,Cheng, Kui
, p. 2041 - 2050 (2018/03/13)
Toll-like receptor 2 (TLR2) can recognize pathogen-associated molecular patterns to defense against invading organisms and has been represents an attractive therapeutic target. Until today, none TLR2 small molecule antagonist have been developed in clinic
Facile synthesis of indole heterocyclic compounds based micellar nano anti-cancer drugs
Ali, Imran,Mukhtar, Sofi Danish,Hsieh, Ming Fa,Alothman, Zeid A.,Alwarthan, Abdulrahman
, p. 37905 - 37914 (2018/11/26)
Facile synthesis of micellar “nano” indole heterocyclic anti-cancer compounds is described. The synthesized compounds (11-23) were characterized by UV-VIS, 1H NMR, FT-IR and mass spectroscopy. The binding energies of DNA-compound adducts varied
Ultrasound-assisted synthesis, anticonvulsant activity, and docking study of indole-appended thiazolidin-4-ones
Nikalje, Anna Pratima G.,Shaikh, Sameer I.,Mulay, Abhineet,Khan, Firoz A. K.,Sangshetti, Jaiprakash N.,Shaikh, Shoaib
, p. 756 - 767 (2016/02/26)
Two series of novel indolyl thiazolidin-4-one derivatives 4a-j and 5a-j were obtained by an ecofriendly synthetic protocol by treating a mixture of Schiff's bases (0.01 mol) with thioglycolic acid or thiolactic acid (0.01 mol) and anhydrous zinc chloride
Microwave assisted synthesis and antimicrobial evaluation of schiff bases of indole-3-aldehyde
Kamaria, Priyanka,Kawathekar,Chaturvedi, Prerna
experimental part, p. 305 - 311 (2012/02/01)
In order to develop new antimicrobial agents, a series of Schiff bases of indole-3-aldehyde were synthesized by microwave assisted synthesis by taking DMF as solvent and evaluated for their antimicrobial activity. All the synthesized compounds were charac
Reaction of 1-(oxiran-2-ylmethyl)-1H-indole-3-carboxaldehyde with amines
Suzdalev, Konstantin F.,Den'Kina, Sophia V.,Starikova, Alena A.,Dvurechensky, Vladimir V.,Kletsky, Mikhail E.,Burov, Oleg N.
scheme or table, p. 231 - 233 (2011/10/18)
Interaction of 1-(oxiran-2-ylmethyl)-1H-indole-3-carboxaldehyde with primary amines occurs at oxirane moiety and leads to b-aminoalcohols. Quantum-chemical calculations show that these products are more stable than possible alternative Schiff bases arisin
