71699-35-9

Usage

InChI:InChI=1/C8H16O2/c1-4-7(9)6(3)8(10)5-2/h6-7,9H,4-5H2,1-3H3/t6-,7+/m0/s1

Upstream product

• 140630-64-4 diethyl (4R)-trans-2-ethyl-2-(3-oxopent-2-yl)-1,3-dioxolan-4,5-dicarboxylate 
• 123-38-6 propionaldehyde 
• 100420-05-1 (4R,5S)-2,2-diethyl-4-methyl-5-phenyl-1,3-oxazolidine 
• 51425-54-8 (Z)-3-trimethylsiloxy-2-pentene 

Relevant academic research and scientific papers

Chiral orthoesters in organic synthesis: Novel reagents for the enantioselective acylation of silylenolethers

Dialkyl trans-2-alkoxy-2-alkyl-1,3-dioxolan-4,5-dicarboxylates and the corresponding N,N,N,N-tetramethyl-4,5-diamides have been prepared respectively from dialkyl tartrates or tartaric acid diamides. They smoothly reacted with silylenolethers in the prese

HIGHLY ENANTIOSELECTIVE SYNTHESIS OF ANTI(THREO)-ALDOLS BY THE ASYMMETRIC ALDOL REACTION UTILIZING A CHIRAL AZAENOLATE

Diastereo- and enantioselective aldol reaction between 3-pentanone and aldehydes is achieved utilizing a chiral oxazolidine derived from 3-pentanone and chiral norephedrine.The reaction of a tin(II) azaenolate generated from the chiral oxazolidine with aldehydes affords predominantly anti(threo)-aldols of high enantiomeric purity.