71702-72-2Relevant academic research and scientific papers
A convenient one-pot synthesis of bis[(E)-4-halostyryl]arene derivatives
Prukala, Wieslaw,Majchrzak, Mariusz,Posala, Krystian,Marciniec, Bogdan
experimental part, p. 3047 - 3052 (2009/04/06)
A new convenient synthetic protocol for the one-pot stereoselective synthesis of bis[(E)-4-bromo(or chloro)styryl]arene derivatives via the sequential reaction of silylative-coupling of 4-halostyrenes with vinylsilanes followed by palladium-catalyzed cross-coupling 4-halostyrylsilanes with diiodoarenes, is described. The reaction leads to symmetrical bis[(E)-4-halostyryl]arene derivatives obtained in a stereocontrolled manner with high efficiency. Georg Thieme Verlag Stuttgart.
